NS 102
NS 102 (CAS: 136623-01-3), a yellow solid with the molecular formula C12H11N3O4 and a molecular weight of 261.23 g/mol, is a key research chemical. It functions as an AMPA/Kainate antagonist, playing a crucial role in neuroscience and cell biology research. This compound is essential for investigating excitatory amino acid neurotransmission and the intricate mechanisms of ionotropic glutamate receptors.
- IUPAC
- 6,7,8,9-Tetrahydro-5-nitro-1H-benz[g]indole-2,3-dione 3-oxime
- Synonyms
- 6,7,8,9-Tetrahydro-5-nitro-1H-benz[g]indole-2,3-dione 3-oxime

Neuroscience Research
NS 102 is utilized to study the roles of AMPA and kainate receptors in synaptic transmission and plasticity. Its antagonist properties help researchers elucidate the function of these ionotropic glutamate receptors in various neurological processes.
Cell Biology Studies
This compound serves as a valuable tool in cell biology for examining signaling pathways regulated by excitatory amino acids. It aids in understanding cellular responses to neurotransmitter activity.
Ion Channel Modulation
NS 102 is employed to investigate the function of ligand-gated ion channels, specifically those activated by glutamate. Research focuses on how these channels are modulated and their impact on cellular excitability.
| Molecular weight | 261.23 |
|---|---|
| Empirical formula | C12H11N3O4 |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: >3 mg/mLH2O: insolublemethanol: insoluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NS 102 used for?
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NS 102 is primarily used in neuroscience and cell biology research as an AMPA/Kainate antagonist to study excitatory amino acid neurotransmission and ionotropic glutamate receptor function.
What is the CAS number and molecular formula for NS 102?
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The CAS number for NS 102 is 136623-01-3, and its molecular formula is C12H11N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies NS 102 as a research-grade chemical. The specific assay and purity are detailed on the product's Certificate of Analysis. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling considerations for NS 102?
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When handling NS 102, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The WGK Germany classification is 3, indicating a high hazard to water.
Is NS 102 a controlled substance?
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The provided data does not indicate that NS 102 is a controlled substance.
How is NS 102 packed, shipped, and exported?
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NS 102 is packed in compliance with international shipping regulations for chemical substances. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for NS 102?
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To request a sample or obtain a quote for NS 102, please contact our sales department through the website or by phone. Our team will respond promptly to your inquiry.
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