NPS2143 hydrochloride
NPS2143 hydrochloride (CAS: 324523-20-8) is a chemical compound with the molecular formula C24H25ClN2O2 · HCl and a molecular weight of 445.38 g/mol. It is supplied as a white to beige powder. This compound is primarily used in cell biology research, specifically in studies involving calcium antagonists and intracellular calcium signaling pathways within cell signaling and neuroscience.
- IUPAC
- 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-benzonitrile hydrochloride (1:1),NPS-2143 hydrochloride,SB-262470-A hydrochloride
- Synonyms
- 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-benzonitrile hydrochloride (1:1)NPS-2143 hydrochlorideSB-262470-A hydrochloride

Calcium Antagonist Research
NPS2143 hydrochloride serves as a valuable tool for investigating the role of calcium channel blockers in various biological systems. Its specific mechanism of action can be explored in diverse cellular models.
Intracellular Calcium Signaling Studies
This compound is utilized to modulate and study the dynamics of intracellular calcium. Researchers can employ it to understand how calcium levels impact cellular functions and signaling cascades.
Cell Biology Investigations
As a reagent in cell biology, NPS2143 hydrochloride aids in understanding cellular processes. It is particularly relevant for experiments focusing on cell physiology and molecular mechanisms.
Neuroscience Research
The compound's involvement in cell signaling makes it relevant for neuroscience applications. It can be used to investigate neuronal function and signaling pathways related to calcium homeostasis.
| Molecular weight | 445.38 |
|---|---|
| Empirical formula | C24H25ClN2O2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 20/21/22-50/53 |
| Safety statements (S) | 36/37-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NPS2143 hydrochloride used for?
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NPS2143 hydrochloride is primarily used in cell biology research, focusing on calcium antagonists, intracellular calcium signaling, cell signaling, and neuroscience.
What is the CAS number and formula for NPS2143 hydrochloride?
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The CAS number is 324523-20-8 and the empirical formula is C24H25ClN2O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies NPS2143 hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should NPS2143 hydrochloride be handled and stored?
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NPS2143 hydrochloride is harmful if swallowed, in contact with skin, or if inhaled, and is very toxic to aquatic life with long-lasting effects. It should be stored at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.
Is NPS2143 hydrochloride a controlled substance?
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The provided data does not indicate that NPS2143 hydrochloride is a controlled substance.
How is NPS2143 hydrochloride packed, shipped, and exported?
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NPS2143 hydrochloride is typically supplied as a powder and is packaged according to international shipping regulations for chemicals. Tech Serve Solutions is a global supplier and exporter.
How can I request a sample or quote for NPS2143 hydrochloride?
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Please contact our sales team through the website to request a sample or a formal quotation for NPS2143 hydrochloride.
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