(Formylmethyl)triphenylphosphonium chloride
(Formylmethyl)triphenylphosphonium chloride (CAS: 62942-43-2) is a crucial organic reagent with the linear formula HCOCH2P(Cl)(C6H5)3 and a molecular weight of 340.78. It serves as a valuable building block in organic synthesis, particularly for C-C bond formation and olefination reactions. Its utility extends to preparing complex molecules through hydroazidation and cycloaddition pathways, making it a key component in advanced chemical synthesis.
- IUPAC
- 2-Oxoethyltriphenylphosphonium chloride
- Synonyms
- 2-Oxoethyltriphenylphosphonium chloride
Hydroazidation Reactions
Serves as a reactant in hydroazidation reactions, facilitating the preparation of alpha-azido alcohols, a class of compounds with significant synthetic utility.
Prodrug Synthesis
Utilised in the preparation of the prodrug (2-hydroxyamino-vinyl)-triphenyl-phosphonium (HVTP), which acts as an inhibitor of peroxidase activity and apoptosis.
Intramolecular Cycloadditions
Employed in intramolecular [4 + 3] cycloaddition reactions, enabling the efficient construction of complex cyclic organic structures.
| Molecular weight | 340.78 |
|---|---|
| Linear formula | HCOCH2P(Cl)(C6H5)3 |
| Assay | ≥97.0% (AT) |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Hydroazidation reactions in preparation of a-azido alcohols1• Preparation of prodrug (2-hydroxyamino-vinyl)-triphenyl-phosphonium (HVTP) inhibitor of peroxidase activity and apoptosis2• Intramolecular [4 + 3] cycloaddition reactions3 |
| Melting point | 209-212 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Formylmethyl)triphenylphosphonium chloride used for?
+
(Formylmethyl)triphenylphosphonium chloride is used as a reactant in hydroazidation reactions for preparing a-azido alcohols, in the synthesis of the prodrug HVTP, and in intramolecular [4 + 3] cycloaddition reactions.
What are the CAS number and formula for (Formylmethyl)triphenylphosphonium chloride?
+
The CAS number is 62942-43-2 and the linear formula is HCOCH2P(Cl)(C6H5)3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (Formylmethyl)triphenylphosphonium chloride with a purity of ≥97.0% (AT). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should (Formylmethyl)triphenylphosphonium chloride be handled safely?
+
This compound is a Danger hazard. It is harmful if swallowed (H302) and causes serious eye damage (H318). Appropriate personal protective equipment, including Eyeshields, Gloves, and a dust mask type N95 (US), must be used. Handle with care and avoid contact with eyes, skin, and clothing. Store at 2-8°C.
How is (Formylmethyl)triphenylphosphonium chloride packed, shipped, and exported?
+
Tech Serve Solutions specialises in the global supply and export of fine chemicals. Products are carefully packaged to ensure integrity during transit and are exported worldwide. Specific packaging details can be provided upon request.
How can I request a quote or sample for (Formylmethyl)triphenylphosphonium chloride?
+
To request a quote or a sample, please visit the Tech Serve Solutions website or contact our sales team directly. We are happy to assist with your chemical sourcing needs.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis