N1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-N1,N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine
N1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-N1,N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine (CAS: 1111625-98-9) is a specialised fluorescent probe with a molecular weight of 496.52. It exhibits high sensitivity and selectivity for zinc ions (Zn²⁺), making it invaluable for quantitative analysis in biological research. Its fluorescent properties enable accurate detection of Zn²⁺ concentrations within specific biological systems.
- IUPAC
- N-(2-(Bis((pyridin-2-yl)methyl)amino)ethyl)-7-nitro-N-((pyridin-2-yl)methyl)benzo[c][1,2,5]oxadiazole-4-amine,NBD-TPEA
- Synonyms
- N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine,1111625-98-9, C26H24N8O3,N-(2-(Bis((pyridin-2-yl)methyl)amino)ethyl)-7-nitro-N-((pyridin-2-yl)methyl)benzo[c][1,2,5]oxadiazole-4-amine,NBD-TPEA
Zinc Ion Detection
This compound is a highly sensitive fluorescent probe for detecting zinc ions (Zn²⁺). It provides a linear response for Zn²⁺ concentrations in the range of 1-10 μM, with good selectivity over other common metal ions.
Biological Research
Utilised for in vivo determination of Zn²⁺ concentrations, particularly in pancreatic β cells and zebra fish larvae, enabling detailed study of cellular zinc homeostasis.
Fluorescent Indicator
Serves as a fluorescent indicator, with excitation at 470 nm and emission at 534 nm, facilitating visual or instrument-based quantification of zinc.
| Molecular weight | 496.52 |
|---|---|
| Empirical formula | C26H24N8O3 |
| Assay | ≥95% |
| Storage temperature | −20°C |
| Application | N1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-N1,N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine has a high sensitivity for zinc ions. Using fluorescent detection, a linear responsive is observed for Zn2+ concentrations in the range of 1-10 μM. It has good selectivity for Zn2+ in the presence of competing metal ions, such as Ca2+, Mg2+, Fe2+, Fe3+, and Mn2+,1 and has been used in vivo to determine Zn2+ concentration in pancreatic β cells1 and zebra fish larvae.2 |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 470 nm; λem 534 nm |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-N1,N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine used for?
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This compound is primarily used as a sensitive and selective fluorescent probe for the detection and quantification of zinc ions (Zn²⁺) in biological research, including in vivo studies.
What is the CAS number and molecular formula?
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The CAS number is 1111625-98-9, and the empirical formula is C26H24N8O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled?
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This chemical is classified as Dangerous. It is toxic if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment and follow safety data sheet guidelines. Store at -20°C.
How is the product packed and exported?
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Products are carefully packed to international standards for safe transit. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for N1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-N1,N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine.
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