N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine 3′-O-succinic acid
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine 3′-O-succinic acid (CAS 74405-46-2) is a modified deoxyguanosine derivative with a molecular weight of 739.77 g/mol. This compound serves as a crucial building block in oligonucleotide synthesis, particularly for research purposes in molecular biology and medicinal chemistry. Its specific structure facilitates the incorporation of modified guanine bases into DNA strands, enabling the study of genetic sequences and the development of novel therapeutic agents.
- Synonyms
- C39H41N5O10
Oligonucleotide Synthesis
This succinic acid derivative is employed as a phosphoramidite or building block in the automated synthesis of DNA oligonucleotides. It allows for the precise incorporation of modified guanine units into synthetic DNA sequences for research applications.
Medicinal Chemistry Research
It is utilized in the development of novel therapeutics and diagnostic tools by enabling the creation of custom DNA sequences with specific functionalities. Its role is primarily in the research and development phases for potential drug discovery.
Molecular Biology Studies
Researchers use this compound to create modified nucleic acids for investigating DNA structure, function, and interactions. This aids in understanding complex biological processes at a molecular level.
| Molecular weight | 739.77 |
|---|---|
| Empirical formula | C39H41N5O10 |
| Assay | ~95% |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 22-26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine 3′-O-succinic acid used for?
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This compound is primarily used as a building block in the synthesis of modified DNA oligonucleotides for research in molecular biology, medicinal chemistry, and genetic studies.
What are the CAS number and formula for this product?
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The CAS number is 74405-46-2, and the empirical formula (Hill notation) is C39H41N5O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of approximately 95%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine 3′-O-succinic acid be handled?
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This compound is labelled with GHS06 (Toxic) and 'Danger' signal word. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation. Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and a P2 respirator. Ensure adequate ventilation.
How is this chemical packed and shipped?
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This chemical is typically stored at -20°C. TSS exports fine chemicals globally, ensuring appropriate packaging and documentation for international shipments.
How can I request a sample or quote?
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Please contact our sales team through our website or by phone to request a sample or a quotation for N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine 3′-O-succinic acid.
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