N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine (CAS 68892-41-1) is a protected nucleoside derivative with the molecular formula C35H37N5O7. It is a key intermediate and building block in oligonucleotide synthesis, particularly for research applications in molecular biology and drug discovery. Stored at -20°C, this compound offers researchers a reliable reagent for advanced nucleic acid research.
- IUPAC
- iBu-DMT-dG
- Synonyms
- iBu-DMT-dGN2-Isobutyryl-2'-deoxyguanosine-5'-(dimethoxytrityl) ether

Oligonucleotide Synthesis
Serves as a crucial phosphoramidite building block for the automated synthesis of DNA and RNA oligonucleotides. Its protected nature facilitates controlled chain elongation in custom nucleic acid synthesis.
Nucleic Acid Research
Utilised in academic and industrial research for developing modified nucleic acids. Essential for studies in genomics, epigenetics, and the creation of novel therapeutic oligonucleotides.
Biochemical Reagent
A high-purity biochemical reagent employed in various laboratory settings. Its specific structure makes it valuable for probing biological mechanisms and developing diagnostic tools.
| Molecular weight | 639.70 |
|---|---|
| Empirical formula | C35H37N5O7 |
| Assay | ~98% |
| Storage temperature | −20°C |
| Melting point | ~150 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine used for?
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This compound is primarily used as a protected building block in oligonucleotide synthesis and for general nucleic acid research, enabling the creation of modified DNA and RNA strands for various scientific investigations.
What is the CAS number and molecular formula?
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The CAS number is 68892-41-1, and the empirical formula is C35H37N5O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of approximately 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This chemical requires careful handling. Recommended personal protective equipment includes eyeshields and gloves, along with a type N95 (US) or type P1 (EN143) respirator filter. Store at -20°C.
How are products from Tech Serve Solutions packed, shipped, and exported?
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Tech Serve Solutions specialises in the global export of fine chemicals, ensuring products are securely packed according to international shipping regulations. We manage all necessary documentation for seamless export to research institutions and companies worldwide.
How can I request a sample or quote for this product?
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To request a sample or a quote, please contact our sales team via the website or direct email, providing the product name and CAS number (68892-41-1).
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