N-p-Tosyl-L-phenylalanine chloromethyl ketone
N-p-Tosyl-L-phenylalanine chloromethyl ketone (CAS 402-71-1), molecular formula C17H18ClNO3S, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- (S)-1-Chloro-3-tosylamido-4-phenyl-2-butanone,(S)-1-Chloro-4-phenyl-3-tosylamido-2-butanone,TPCK,Tosyl-L-phenylalanyl-chloromethane
| Molecular weight | 351.85 |
|---|---|
| Empirical formula | C17H18ClNO3S |
| Assay | ≥97% (TLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >10 mg/mL (stable for several months at 4°C.)ethanol: soluble20 mg/mL (stable for several months at 4°C. Stock solutions (10 mM in methanol or ethanol) are stable for several months at 4°C.) |
| Storage temperature | −20°C |
| Melting point | 106-108 °C(lit.) |
| Application | Irreversible inhibitor of certain serine proteases; used to inhibit chymotrypsin in preparations of trypsin. |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NFKB1(4790), NKAP(79576), NKRF(55922), NOS2(4843), PTGS2(5743) |
|---|---|
| Potency | 10-100 μM effective concentration |
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-p-Tosyl-L-phenylalanine chloromethyl ketone?
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N-p-Tosyl-L-phenylalanine chloromethyl ketone (CAS 402-71-1), molecular formula C17H18ClNO3S, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to USP, BP and EP standards.
What grades of N-p-Tosyl-L-phenylalanine chloromethyl ketone does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-p-Tosyl-L-phenylalanine chloromethyl ketone in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of N-p-Tosyl-L-phenylalanine chloromethyl ketone?
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N-p-Tosyl-L-phenylalanine chloromethyl ketone has CAS number 402-71-1 and molecular formula C17H18ClNO3S. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for N-p-Tosyl-L-phenylalanine chloromethyl ketone?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of N-p-Tosyl-L-phenylalanine chloromethyl ketone ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should N-p-Tosyl-L-phenylalanine chloromethyl ketone be stored?
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Store N-p-Tosyl-L-phenylalanine chloromethyl ketone in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is N-p-Tosyl-L-phenylalanine chloromethyl ketone used for?
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N-p-Tosyl-L-phenylalanine chloromethyl ketone is used in biochemicals & reagents applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for N-p-Tosyl-L-phenylalanine chloromethyl ketone?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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