N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride
N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride (CAS: 117961-27-0) is a fluorogenic peptide substrate with the molecular formula C30H37N7O7S · HCl and a molecular weight of 676.18 g/mol. This compound serves as a valuable reagent in biochemical research, primarily for the detection and quantification of specific enzyme activities. Its structure allows for sensitive assays, making it a key tool in studying enzymatic pathways.
Enzyme Activity Assays
Used as a fluorogenic substrate to detect and quantify the activity of specific proteases, particularly thrombin. The release of 7-amido-4-methylcoumarin upon enzymatic cleavage provides a sensitive fluorescent signal for enzyme kinetics studies.
Biochemical Research
Applicable in cell biology and cell signaling research for investigating enzyme function and interactions. Its specificity makes it useful for understanding complex biological pathways involving proteases.
Neuroscience Studies
Can be employed in neuroscience research to study enzymes involved in neuronal signaling pathways. The fluorogenic nature allows for real-time monitoring of enzymatic activity in biological samples.
Coagulation Research
As a substrate for thrombin, it is useful in research related to the coagulation cascade and blood clotting mechanisms. It aids in studying the kinetics and inhibition of thrombin activity.
| Molecular weight | 676.18 |
|---|---|
| Empirical formula | C30H37N7O7S · HCl |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride used for?
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This compound is primarily used as a fluorogenic peptide substrate for the detection and quantification of protease activity, particularly thrombin, in biochemical and cell biology research.
What are the CAS number and molecular formula?
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The CAS number is 117961-27-0, and the molecular formula is C30H37N7O7S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research purposes. Specific assay and purity information can be found on the product's Certificate of Analysis. This product is not intended for USP, BP, EP, or pharmaceutical use.
What are the safety and handling precautions?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance has a WGK Germany rating of 3, indicating it is hazardous to water.
How is the product shipped and exported?
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N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride is typically stored at -20°C. TSS is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or obtain a quotation for N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride.
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