N-Boc-4-methoxyaniline
N-Boc-4-methoxyaniline (CAS: 18437-68-8; Formula: C12H17NO3; Molar Mass: 223.27 g/mol) is a protected aniline derivative. It serves as a valuable building block in organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. The tert-butoxycarbonyl (Boc) protecting group allows for selective manipulation of the amine functionality during multi-step synthetic pathways.
- IUPAC
- 1-(Boc-amino)-4-methoxybenzene,4-Methoxyphenyl)carbamic acid tert-butyl ester,N-(tert-Butoxycarbonyl)-4-methoxyaniline,N-Boc-p-anisidine,tert-Butyl 4-methoxycarbanilate,tert-Butyl N-(4-methoxyphenyl)carbamate
- Synonyms
- 1-(Boc-amino)-4-methoxybenzene4-Methoxyphenyl)carbamic acid tert-butyl esterN-(tert-Butoxycarbonyl)-4-methoxyanilineN-Boc-p-anisidinetert-Butyl 4-methoxycarbanilatetert-Butyl N-(4-methoxyphenyl)carbamate

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of diverse organic compounds. Its protected amine function enables controlled reactions in complex molecular construction.
Pharmaceutical Research
A useful building block for the preparation of novel pharmaceutical candidates. It facilitates the introduction of the methoxyaniline moiety into potential drug molecules.
Agrochemical Development
Employed in the research and development of new agrochemicals. Its structural features can be incorporated into molecules designed for crop protection applications.
| Molecular weight | 223.27 |
|---|---|
| Empirical formula | C12H17NO3 |
| Assay | 97% |
| Melting point | 93-98 °C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-52 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-4-methoxyaniline used for?
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N-Boc-4-methoxyaniline is primarily used as a building block in organic synthesis, particularly in pharmaceutical and agrochemical research, due to its protected amine functionality.
What is the CAS number and chemical formula for N-Boc-4-methoxyaniline?
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The CAS number for N-Boc-4-methoxyaniline is 18437-68-8, and its chemical formula is C12H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-4-methoxyaniline with an assay of 97%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should N-Boc-4-methoxyaniline be handled?
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N-Boc-4-methoxyaniline is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, avoiding ingestion, inhalation, and contact with skin and eyes. Store in a cool, dry, well-ventilated area.
Is N-Boc-4-methoxyaniline a controlled substance?
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Based on the provided data, there is no indication that N-Boc-4-methoxyaniline is a controlled substance.
How is N-Boc-4-methoxyaniline packed and shipped?
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N-Boc-4-methoxyaniline is carefully packed according to industry standards to ensure safe transit. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for N-Boc-4-methoxyaniline?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (18437-68-8).
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