N-Boc-4-isothiocyanatobutylamine

CAS 247035-47-8C10H18N2O2SOrganic Building Blocks

N-Boc-4-isothiocyanatobutylamine (CAS: 247035-47-8; C10H18N2O2S) is a versatile organic compound featuring a protected amine and an isothiocyanate functional group. This structure makes it valuable in chemical synthesis and chemical biology for introducing specific functionalities. With a molecular weight of 230.33 g/mol, it serves as a key building block in the development of complex molecules and bioconjugates.

IUPAC: tert-Butyl N-(4-isothiocyanatobutyl)carbamate,Boc-4-aminobutyl isothiocyanate
Synonyms: tert-Butyl N-(4-isothiocyanatobutyl)carbamateBoc-4-aminobutyl isothiocyanate

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N-Boc-4-isothiocyanatobutylamine (C10H18N2O2S) — chemical structure, CAS 247035-47-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Bifunctional LinkersBuilding BlocksChemical BiologyChemical SynthesisLinkers and CrosslinkersOrganic Building BlocksSulfur Compounds

01 /Applications

Chemical Synthesis

Utilised as a building block in organic synthesis to construct more complex molecular architectures. The presence of both a protected amine and an isothiocyanate group allows for sequential reactions and diverse derivatization.

Bioconjugation

Its bifunctional nature makes it suitable for conjugating biomolecules. The isothiocyanate group can react with amine groups on proteins or peptides, while the Boc-protected amine can be deprotected and further functionalized.

Linker Chemistry

Acts as a linker in the preparation of various chemical constructs. It enables the bridging of different molecular entities through controlled chemical reactions.

02 /Properties

Molecular weight	230.33
Empirical formula	C10H18N2O2S
Assay	≥97.0%
Density	1.067 g/mL at 20 °C(lit.)
Refractive index	n20/D 1.504
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H334May cause allergy or asthma symptoms if inhaled

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P342

Protective equipment	Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	42
Safety statements (S)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

247035-47-8

MDL number

MFCD01862958

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-Boc-4-isothiocyanatobutylamine used for?

N-Boc-4-isothiocyanatobutylamine is primarily used as a building block in organic synthesis and for bioconjugation applications, enabling the creation of complex molecules and the functionalization of biomolecules.

What are the CAS number and formula for N-Boc-4-isothiocyanatobutylamine?

The CAS number is 247035-47-8, and the molecular formula is C10H18N2O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies N-Boc-4-isothiocyanatobutylamine with an assay of ≥97.0%. We do not represent this product as USP, BP, or EP grade.

How should N-Boc-4-isothiocyanatobutylamine be handled?

This compound is classified as Danger, with hazard statement H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled). Handle with appropriate personal protective equipment, including eyeshields, faceshields, and gloves, in a well-ventilated area. Avoid inhalation.