N-Boc-4-iodoaniline
N-Boc-4-iodoaniline (CAS: 159217-89-7), with the molecular formula C11H14INO2 and a molecular weight of 319.14 g/mol, is a crucial organic compound. It serves as a protected amine and a valuable building block in organic synthesis. Its structure, featuring an iodine atom and a Boc-protected amino group on an aniline ring, makes it particularly useful in cross-coupling reactions and the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
- IUPAC
- (4-Iodophenyl)carbamic acid tert-butyl ester,N-tert-Butoxycarbonyl)-4-iodoaniline,tert-Butyl (4-iodophenyl)carbamate
- Synonyms
- (4-Iodophenyl)carbamic acid tert-butyl estertert-Butyl (4-iodophenyl)carbamateN-(tert-Butoxycarbonyl)-4-iodoaniline
Pharmaceutical Synthesis Intermediate
N-Boc-4-iodoaniline is extensively used as a key intermediate in the multi-step synthesis of various pharmaceutical compounds. The iodine atom facilitates Suzuki, Stille, and Sonogashira coupling reactions, enabling the formation of new carbon-carbon bonds.
Organic Building Block
This compound functions as a versatile building block for constructing more complex organic molecules. The tert-butoxycarbonyl (Boc) protecting group can be selectively removed under acidic conditions, revealing the primary amine for further functionalization.
Material Science Research
It can be employed in the research and development of novel materials, such as organic semiconductors or functional polymers, where precisely controlled aromatic structures are required.
Agrochemical Development
N-Boc-4-iodoaniline may serve as a precursor in the synthesis of new agrochemicals, contributing to the development of crop protection agents.
| Molecular weight | 319.14 |
|---|---|
| Empirical formula | C11H14INO2 |
| Assay | 95% |
| Melting point | 144-148 °C |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-43-50 |
| Safety statements (S) | 36/37-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-4-iodoaniline used for?
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N-Boc-4-iodoaniline is primarily used as a key intermediate in pharmaceutical synthesis and as a versatile building block in organic chemistry for creating complex molecules and in material science research.
What are the CAS number and molecular formula for N-Boc-4-iodoaniline?
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The CAS number for N-Boc-4-iodoaniline is 159217-89-7, and its molecular formula is C11H14INO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-4-iodoaniline with a minimum assay of 95%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeia standards.
What are the main safety considerations when handling N-Boc-4-iodoaniline?
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N-Boc-4-iodoaniline is classified with GHS07 and GHS09 symbols, carrying the signal word 'Warning'. It is harmful if swallowed (H302), may cause an allergic skin reaction (H317), and is very toxic to aquatic life with long-lasting effects (H410). Handle with appropriate personal protective equipment in a well-ventilated area, and avoid release to the environment.
How is N-Boc-4-iodoaniline shipped and exported?
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N-Boc-4-iodoaniline is shipped and exported according to international regulations, including UN 3077, Class 9, Packing Group III for environmentally hazardous substances. Please contact us for specific shipping details.
How can I request a sample or a quote for N-Boc-4-iodoaniline?
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To request a sample or a quote for N-Boc-4-iodoaniline, please use the 'Request Sample' or 'Get Quote' buttons on our product page, or contact our sales team directly.
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