N-Boc-4-isothiocyanatoaniline
N-Boc-4-isothiocyanatoaniline (CAS: 89631-75-4), with the molecular formula C12H14N2O2S and a molecular weight of 250.32 g/mol, is a key organic building block. This compound serves as a versatile reagent in chemical synthesis, particularly for introducing the isothiocyanate group for conjugation and modification reactions. It is widely used in chemical biology and as a linker in various scientific research applications.
- IUPAC
- tert-Butyl N-(4-isothiocyanatophenyl)carbamate
Bioconjugation Reagent
N-Boc-4-isothiocyanatoaniline can be employed to covalently link molecules to biomolecules such as proteins or peptides. The isothiocyanate group reacts readily with primary amines under mild conditions, facilitating bioconjugation.
Chemical Synthesis Intermediate
This compound acts as a valuable intermediate in the synthesis of more complex organic molecules. Its bifunctional nature allows for sequential reactions, making it useful in the construction of diverse chemical structures.
Material Science Applications
The isothiocyanate functionality can be used to modify surfaces or polymers, introducing new properties or enabling further functionalization in material science research.
Diagnostic Reagent Development
It may be used in the development of diagnostic reagents where specific chemical linkages are required for assay development or probe construction.
| Molecular weight | 250.32 |
|---|---|
| Empirical formula | C12H14N2O2S |
| Assay | ≥98.0% (HPLC) |
| Melting point | 109-114 °C |
Hazard statements
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 42 |
| Safety statements (S) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-4-isothiocyanatoaniline used for?
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N-Boc-4-isothiocyanatoaniline is primarily used as a versatile organic building block and reagent in chemical synthesis, bioconjugation, and material science. It is particularly useful for introducing isothiocyanate functionalities and for creating linkers.
What are the CAS number and molecular formula?
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The CAS number for N-Boc-4-isothiocyanatoaniline is 89631-75-4, and its molecular formula is C12H14N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-4-isothiocyanatoaniline with a purity of ≥98.0% (HPLC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should N-Boc-4-isothiocyanatoaniline be handled safely?
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Due to potential respiratory and skin sensitization hazards (H317, H334), handle N-Boc-4-isothiocyanatoaniline with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shield, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the Safety Data Sheet for full details.
How is N-Boc-4-isothiocyanatoaniline shipped or exported?
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Tech Serve Solutions, a specialist global supplier and exporter, ships and exports N-Boc-4-isothiocyanatoaniline in compliance with all relevant regulations for chemical products. Specific packaging details can be provided upon request.
How can I request a sample or quote for N-Boc-4-isothiocyanatoaniline?
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To request a sample or a quotation for N-Boc-4-isothiocyanatoaniline, please contact our sales department via the website or by phone, providing your details and the required quantity.
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