N-Boc-4-pentyne-1-amine
N-Boc-4-pentyne-1-amine (CAS: 151978-50-6; Formula: C10H17NO2) is a protected amine featuring a terminal alkyne functional group. This building block is valuable in organic synthesis, chemical biology, and conjugation chemistry. Its protected amine and alkyne functionalities allow for orthogonal chemical modifications. It is commonly employed in the synthesis of complex molecules and for bioconjugation applications, offering precise control over molecular assembly.
- IUPAC
- 4-Pentynylcarbamic acid tert-butyl ester,N-Boc-5-amino-1-pentyne,tert-Butyl (4-pentynyl)carbamate
- Synonyms
- tert-Butyl (4-pentynyl)carbamate4-Pentynylcarbamic acid tert-butyl esterN-Boc-5-amino-1-pentyne
Organic Synthesis
Serves as a versatile building block for constructing complex organic molecules. The terminal alkyne and Boc-protected amine enable selective functionalisation in multi-step synthetic pathways.
Chemical Biology
Facilitates the introduction of alkyne handles into biomolecules or for creating molecular probes. This is crucial for applications like click chemistry in biological systems.
Conjugation Chemistry
The terminal alkyne is ideal for copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, enabling efficient conjugation to azide-containing partners.
Peptide and Drug Discovery
Used in the modification of peptides or the synthesis of novel drug candidates. The protected amine allows for controlled peptide elongation or the incorporation of alkyne functionalities into potential therapeutics.
| Molecular weight | 183.25 |
|---|---|
| Empirical formula | C10H17NO2 |
| Assay | ≥95% (GC) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-4-pentyne-1-amine used for?
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N-Boc-4-pentyne-1-amine is primarily used as a building block in organic synthesis, chemical biology, and conjugation chemistry, particularly for introducing alkyne and protected amine functionalities into molecules for further modification or bioconjugation.
What is the CAS number and formula for N-Boc-4-pentyne-1-amine?
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The CAS number for N-Boc-4-pentyne-1-amine is 151978-50-6, and its molecular formula is C10H17NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-4-pentyne-1-amine with a purity of ≥95% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Boc-4-pentyne-1-amine be handled?
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N-Boc-4-pentyne-1-amine is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure adequate ventilation and avoid breathing vapours.
Is N-Boc-4-pentyne-1-amine a controlled substance?
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The provided data does not indicate that N-Boc-4-pentyne-1-amine is a controlled substance.
How is this chemical packed and exported?
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This chemical is packed and exported according to international shipping regulations for hazardous materials. It is classified under UN 2735, Class 8, Packing Group II.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by calling us directly. Provide the product name and CAS number for prompt service.
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