N-Boc-3-methoxyaniline
N-Boc-3-methoxyaniline (CAS 60144-52-7) is a protected amine with the molecular formula C12H17NO3 and a molecular weight of 223.27 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the introduction of protected methoxyaniline moieties into more complex molecules. Its protected amine functionality allows for selective reactions elsewhere in a molecule, making it a useful intermediate in pharmaceutical and fine chemical research and development.
- IUPAC
- 1-(Boc-amino)-3-methoxybenzene,N-Boc-m-anisidine,tert-Butyl 3-methoxyphenylcarbamate

Organic Synthesis Intermediate
N-Boc-3-methoxyaniline is widely employed as a key intermediate in multi-step organic syntheses. Its Boc-protected amine group can be readily deprotected under specific conditions, facilitating further functionalization or coupling reactions in the synthesis of complex organic structures.
Pharmaceutical Research
This compound finds application in the research and development of new pharmaceutical agents. It can be incorporated into the synthesis pathways of potential drug candidates, where the methoxyaniline scaffold is a desired structural feature.
Fine Chemical Production
As a versatile building block, N-Boc-3-methoxyaniline is utilised in the production of various fine chemicals. Its specific structure and reactivity make it suitable for the synthesis of specialised organic compounds for diverse industrial applications.
| Molecular weight | 223.27 |
|---|---|
| Empirical formula | C12H17NO3 |
| Assay | 97% |
| Melting point | 55-60 °C |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-52 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-3-methoxyaniline used for?
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N-Boc-3-methoxyaniline (CAS 60144-52-7) is primarily used as a protected amine building block in organic synthesis, particularly in the research and development of pharmaceuticals and fine chemicals. Its Boc-protected group allows for selective synthetic transformations.
What are the CAS number and formula for N-Boc-3-methoxyaniline?
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The CAS number for N-Boc-3-methoxyaniline is 60144-52-7, and its molecular formula is C12H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-3-methoxyaniline with a minimum assay of 97%. This product is intended for laboratory and research purposes and is not supplied as USP, EP, BP, or any other pharmacopoeia grade.
How should N-Boc-3-methoxyaniline be handled safely?
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N-Boc-3-methoxyaniline is classified as a Warning. It is harmful if swallowed (H302) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including gloves and eye protection, and avoid ingestion or contact with eyes. Ensure good ventilation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
Can you export N-Boc-3-methoxyaniline?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including N-Boc-3-methoxyaniline, and can facilitate international shipments.
How can I request a sample or quote for N-Boc-3-methoxyaniline?
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To request a sample or a quotation for N-Boc-3-methoxyaniline, please use the contact form on our website or contact our sales department directly with your requirements.
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