N-Boc-2-methoxyaniline
N-Boc-2-methoxyaniline (CAS: 154150-18-2), with the molecular formula C12H17NO3 and a molecular weight of 223.27 g/mol, is a protected amine derivative. This compound serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and fine chemical industries. Its structure, featuring a Boc-protected amino group and a methoxy substituent on an aniline core, allows for selective reactions and the construction of more complex molecular architectures.
- IUPAC
- 1-(Boc-amino)-2-methoxybenzene,N -(2-Methoxyphenyl)carbamic acid tert-butyl ester,tert-Butyl 2-methoxyphenylcarbamate,Boc-o-anisidine
- Synonyms
- tert-Butyl 2-methoxyphenylcarbamateN-(2-Methoxyphenyl)carbamic acid tert-butyl esterBoc-o-anisidine1-(Boc-amino)-2-methoxybenzene
Organic Synthesis Intermediate
N-Boc-2-methoxyaniline is frequently employed as a key intermediate in the synthesis of complex organic molecules. The tert-butoxycarbonyl (Boc) protecting group facilitates selective functionalization of the aniline nitrogen, enabling controlled downstream reactions.
Pharmaceutical Research and Development
This compound finds application in the R&D of new pharmaceutical agents. Its utility lies in its role as a precursor for biologically active compounds, where the methoxy and protected amino functionalities can be elaborated upon.
Fine Chemical Manufacturing
As a versatile building block, N-Boc-2-methoxyaniline is utilised in the manufacturing of various fine chemicals. Its specific structural features make it suitable for creating diverse chemical entities for research and commercial purposes.
| Molecular weight | 223.27 |
|---|---|
| Empirical formula | C12H17NO3 |
| Assay | 97% |
| Melting point | 33.5-35.0 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-2-methoxyaniline used for?
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N-Boc-2-methoxyaniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and fine chemicals. Its protected amine and methoxy functionalities allow for selective chemical transformations.
What is the CAS number and molecular formula for N-Boc-2-methoxyaniline?
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The CAS number for N-Boc-2-methoxyaniline is 154150-18-2, and its molecular formula is C12H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-2-methoxyaniline with an assay of 97%. This product is not represented as USP, EP, BP, or any other pharmacopoeia grade.
What are the safety considerations when handling N-Boc-2-methoxyaniline?
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N-Boc-2-methoxyaniline is classified as a Warning substance. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment and ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for full details.
How is N-Boc-2-methoxyaniline packed, shipped, and exported?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging and compliance with international shipping regulations for chemical products.
How can I request a quote or sample for N-Boc-2-methoxyaniline?
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To request a quote or sample of N-Boc-2-methoxyaniline, please contact our sales department through the website or by phone, providing your specific requirements and contact information.
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