N-Boc-2-isothiocyanatoethylamine
N-Boc-2-isothiocyanatoethylamine (CAS: 137743-46-5; Formula: C8H14N2O2S; MW: 202.27) is a valuable organic building block and bifunctional linker. Its structure incorporates a Boc-protected amine and an isothiocyanate group, enabling selective reactions in chemical synthesis. This compound is primarily utilized in the construction of 2-alkylamino-1-imidazolines, serving as a key intermediate in various research and development applications within chemical biology and organic synthesis.
- IUPAC
- tert-Butyl N-(2-isothiocyanatoethyl)carbamate
- Synonyms
- tert-Butyl N-(2-isothiocyanatoethyl)carbamate
Synthesis of 2-Alkylamino-1-imidazolines
N-Boc-2-isothiocyanatoethylamine serves as a crucial precursor in the synthesis of 2-alkylamino-1-imidazolines. This reaction pathway allows for the introduction of specific side chains and functional groups, enabling the creation of diverse molecular scaffolds.
Chemical Biology Research
As a bifunctional linker, this compound is employed in chemical biology to conjugate molecules or create probes. Its distinct reactive groups allow for controlled attachment to biomolecules or other chemical entities for studying biological processes.
Organic Synthesis Building Block
The compound functions as a versatile building block in organic synthesis. The Boc-protected amine and the isothiocyanate moiety offer orthogonal reactivity, facilitating multi-step synthetic routes towards complex organic molecules.
| Molecular weight | 202.27 |
|---|---|
| Empirical formula | C8H14N2O2S |
| Assay | ≥98.0% (GC) |
| Application | Used in the synthesis of 2-alkylamino-1-imidazolines1,2 |
| Melting point | 92-96 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-2-isothiocyanatoethylamine used for?
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N-Boc-2-isothiocyanatoethylamine is used in the synthesis of 2-alkylamino-1-imidazolines and as a building block in chemical synthesis and chemical biology research.
What is the CAS number and formula for N-Boc-2-isothiocyanatoethylamine?
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The CAS number for N-Boc-2-isothiocyanatoethylamine is 137743-46-5, and its empirical formula is C8H14N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-2-isothiocyanatoethylamine with a purity of ≥98.0% (GC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should N-Boc-2-isothiocyanatoethylamine be handled safely?
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N-Boc-2-isothiocyanatoethylamine is classified as a danger with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, should be used. Handle in a well-ventilated area and avoid inhalation of dust.
Is N-Boc-2-isothiocyanatoethylamine a controlled substance?
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The provided data does not indicate that N-Boc-2-isothiocyanatoethylamine is a controlled substance.
How is N-Boc-2-isothiocyanatoethylamine packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions professionally packs, ships, and exports chemicals like N-Boc-2-isothiocyanatoethylamine, adhering to international shipping regulations for research chemicals.
How can I request a sample or quote for N-Boc-2-isothiocyanatoethylamine?
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To request a sample or quote for N-Boc-2-isothiocyanatoethylamine, please contact our sales team through the website or by phone. Our experts will be pleased to assist you.
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