Methyl (S)-(−)-4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate

CAS 307532-01-0(CH3)3CSi(CH3)2OCH2CH2CH(OH)CO2CH3Chemical Synthesis

Methyl (S)-(−)-4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate (CAS: 307532-01-0) is a chiral building block with a molecular weight of 248.39 g/mol. This ester features a hydroxyl group and a silyl-protected hydroxyl, making it a versatile intermediate for complex organic synthesis. It is primarily utilised in asymmetric synthesis and general chemical manufacturing processes, offering a defined stereochemical centre for targeted molecular construction.

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Methyl (S)-(−)-4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate ((CH3)3CSi(CH3)2OCH2CH2CH(OH)CO2CH3) — chemical structure, CAS 307532-01-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksEstersOrganic Building Blocks

01 /Applications

Chiral Building Block

This compound serves as a valuable chiral synthon in the construction of stereochemically complex molecules. Its defined (S)-configuration is crucial for introducing specific chirality into target structures.

Asymmetric Synthesis

Utilised in asymmetric synthesis pathways, this molecule facilitates the stereoselective creation of enantiomerically pure or enriched compounds, vital for pharmaceutical and agrochemical research.

Intermediate in Organic Synthesis

The presence of both a protected hydroxyl and a free hydroxyl group, alongside an ester functionality, allows for diverse synthetic transformations and functional group interconversions in multi-step syntheses.

02 /Properties

Molecular weight	248.39
Linear formula	(CH3)3CSi(CH3)2OCH2CH2CH(OH)CO2CH3
Assay	≥94%
Density	0.979 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.493(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Flash point	82 °C / 179.6 °F
Transport (UN / ADR)	UN 1993 / PGIII
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

307532-01-0

MDL number

MFCD07776971

PubChem substance

24883576

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Methyl (S)-(−)-4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate used for?

Methyl (S)-(−)-4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate is used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis.

What is the CAS number and formula for this compound?

The CAS number is 307532-01-0. The linear formula is (CH₃)₃CSi(CH₃)₂OCH₂CH₂CH(OH)CO₂CH₃.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of ≥94%. We do not represent this product as USP/BP/EP grade.

How should this chemical be handled safely?

This compound is classified as a Warning, causing serious eye irritation (H319). Ensure use with eyeshields and gloves. A half-mask respirator is recommended. Handle in a well-ventilated area. Refer to the safety data sheet for full handling instructions.

Can Tech Serve Solutions export this chemical?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product, adhering to all relevant shipping regulations.

How can I request a sample or quote?

To request a sample or a quote for Methyl (S)-(−)-4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate, please contact our sales team through the website or by phone.