Methyl (Z)-oct-2-enoate-3-boronic acid pinacol ester

CAS 352534-74-8C15H27BO4Chemical Synthesis

Methyl (Z)-oct-2-enoate-3-boronic acid pinacol ester (CAS: 352534-74-8) is an organoboron compound with the molecular formula C15H27BO4 and a molecular weight of 282.18. This alkenyl boronate ester serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure facilitates the introduction of specific unsaturated ester functionalities into target molecules.

IUPAC: Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-octenoate
Synonyms: Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-octenoate

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Methyl (Z)-oct-2-enoate-3-boronic acid pinacol ester (C15H27BO4) — chemical structure, CAS 352534-74-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Alkenyl Boronate EstersBoronate EstersChemical SynthesisOrganometallic Reagents

01 /Applications

Organic Synthesis Intermediate

This compound is utilised as a key intermediate in the synthesis of complex organic molecules. Its boronate ester functionality allows for participation in Suzuki-Miyaura coupling and other palladium-catalysed cross-coupling reactions.

Cross-Coupling Reactions

It serves as a versatile coupling partner in the formation of carbon-carbon bonds. The Z-alkene stereochemistry is retained during many coupling processes, enabling stereoselective synthesis.

Pharmaceutical Intermediate Development

The compound can be employed in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates, where precise structural incorporation is required.

02 /Properties

Molecular weight	282.18
Empirical formula	C15H27BO4
Boiling point	287-288 °C(lit.)
Density	0.965 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.455(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

352534-74-8

MDL number

MFCD03093978

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Methyl (Z)-oct-2-enoate-3-boronic acid pinacol ester used for?

Methyl (Z)-oct-2-enoate-3-boronic acid pinacol ester is primarily used as an intermediate in organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds and the introduction of specific unsaturated ester functionalities.

What are the CAS number and formula for this compound?

The CAS number is 352534-74-8 and the molecular formula is C15H27BO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and laboratory use. The specific grade and purity are available upon request and do not equate to pharmacopoeia standards such as USP, BP, or EP.

What are the safety and handling precautions for this chemical?

Handling this chemical requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with WGK 2 in Germany, indicating it is hazardous to water.