Levocabastine hydrochloride
Levocabastine hydrochloride (CAS 79547-78-7), with the molecular formula C26H29N2O2F·HCl and a molecular weight of 456.98 g/mol, is a potent H1 receptor antagonist. This white solid is primarily utilised in research as a tool compound for investigating histamine signalling pathways and as a potential therapeutic agent in areas related to allergy and inflammation. Its specific chemical structure makes it valuable in biochemical and cell biology studies.
- IUPAC
- Levophta,Levostin,R50547,[3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid
- Synonyms
- [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid

Histamine Receptor Antagonist Research
Levocabastine hydrochloride serves as a selective H1 receptor antagonist, valuable for in vitro and in vivo studies investigating the role of histamine in physiological and pathological processes. It aids in understanding allergic responses and inflammation pathways.
Neuroscience Research Tool
As a modulator of GPCRs, this compound is applied in neuroscience research to explore cell signaling mechanisms and the function of neurotransmitter systems. Its specific interactions contribute to understanding neurological pathways.
Biochemical and Cell Biology Studies
Utilised as a bioactive small molecule, Levocabastine hydrochloride is employed in biochemical assays and cell-based studies to probe cellular functions and signaling cascades. Its well-defined activity profile supports experimental design.
| Molecular weight | 456.98 |
|---|---|
| Empirical formula | C26H29N2O2F·HCl |
| Assay | ≥99% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble ~10 mg/mL |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Levocabastine hydrochloride used for?
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Levocabastine hydrochloride is used in research as a histamine H1 receptor antagonist for studying allergic responses, inflammation, and neurological pathways. It is a valuable tool in biochemical and cell biology investigations.
What is the CAS number and molecular formula for Levocabastine hydrochloride?
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The CAS number for Levocabastine hydrochloride is 79547-78-7, and its molecular formula is C26H29N2O2F·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Levocabastine hydrochloride with an assay of ≥99% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the specifications.
How should Levocabastine hydrochloride be handled safely?
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Levocabastine hydrochloride is classified as a Warning. It is a skin, eye, and respiratory irritant (H315, H319, H335). When handling, wear appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US). Ensure adequate ventilation and avoid dust formation.
Is Levocabastine hydrochloride a controlled substance?
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The provided data does not indicate that Levocabastine hydrochloride is a controlled substance.
How is Levocabastine hydrochloride packed and exported?
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Levocabastine hydrochloride is typically supplied as a white solid. TSS exports chemicals globally, adhering to all necessary regulations for safe and compliant shipment.
How can I request a sample or quote for Levocabastine hydrochloride?
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To request a sample or quote for Levocabastine hydrochloride, please use the contact form on our website or reach out to our sales department directly.
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