Levofloxacin
Levofloxacin (CAS: 100986-85-4), with the molecular formula C18H20FN3O4 and a molecular weight of 361.37, is a broad-spectrum fluoroquinolone antibiotic. It is primarily utilised in research settings for studies investigating pharmacokinetic properties, antibiotic resistance mechanisms, and strategies for resistance prevention. Levofloxacin acts by inhibiting bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication, transcription, repair, and recombination.
- IUPAC
- (−)-Ofloxacin
- Synonyms
- (−)-Ofloxacin
Pharmacokinetic Studies
Levofloxacin serves as a valuable tool in research for understanding drug absorption, distribution, metabolism, and excretion (ADME) properties. Its use allows for detailed pharmacokinetic profiling in various experimental models.
Antibiotic Resistance Research
This compound is employed in investigations into the mechanisms by which bacteria develop resistance to fluoroquinolone antibiotics. Studying Levofloxacin helps elucidate resistance pathways and identify potential targets for new therapeutic strategies.
Resistance Prevention Studies
Researchers utilise Levofloxacin to explore methods and agents that can prevent or overcome antibiotic resistance. This application is critical for developing strategies to preserve the efficacy of existing antibiotics.
| Molecular weight | 361.37 |
|---|---|
| Empirical formula | C18H20FN3O4 |
| Assay | ≥98.0% (HPLC) |
| Application | Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic 1, antibiotic resistance 2 , and resistance prevention 3studies. |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
- H361D
- H362May cause harm to breast-fed children
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P263
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22-42/43-64 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... KCNH1(3756) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Levofloxacin used for?
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Levofloxacin is used in research for pharmacokinetic, antibiotic resistance, and resistance prevention studies.
What is the CAS number and formula for Levofloxacin?
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The CAS number for Levofloxacin is 100986-85-4, and its empirical formula is C18H20FN3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Levofloxacin with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade unless explicitly stated.
What are the safety and handling precautions for Levofloxacin?
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Levofloxacin is classified with GHS07 and GHS08 symbols, and a Danger signal word. It carries hazard statements H302 (Harmful if swallowed), H317 (May cause an allergic skin reaction), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), H361d (Suspected of damaging the unborn child), and H362 (May harm breast-fed children). Appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, faceshields, and gloves is recommended. Handle with extreme caution, avoiding inhalation, ingestion, and skin contact. Consult the Safety Data Sheet (SDS) for full details.
How is Levofloxacin packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with all relevant international regulations for safe transport.
How can I request a sample or quote for Levofloxacin?
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To request a sample or a quote for Levofloxacin, please contact our sales team through the website or by phone.
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