Leupeptin hemisulfate salt
Leupeptin hemisulfate salt (CAS: 103476-89-7; Formula: C20H38N6O4 · 1/2H2SO4; MW: 475.59) is a protease inhibitor commonly used in biochemical research. It functions as an effective inhibitor of serine and cysteine proteases. Supplied by Tech Serve Solutions, this compound is valuable for preventing protein degradation during extraction and purification processes, ensuring the integrity of sensitive biological samples. Its primary applications lie within molecular biology and protein chemistry laboratories.
- IUPAC
- Acetyl-Leu-Leu-Arg-al,N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt

Protease Inhibition
Leupeptin hemisulfate salt is a potent inhibitor of serine and cysteine proteases. It is widely used to prevent protein degradation during the isolation and purification of cellular proteins.
Biochemical Research
This compound serves as a critical reagent in various biochemical research applications. It helps maintain the stability and integrity of proteins in experimental settings, particularly in cell lysis and sample preparation.
Enzyme Studies
Researchers utilise Leupeptin hemisulfate salt to study the specific roles of serine and cysteine proteases in biological pathways. It aids in characterising enzymatic activity and understanding protein processing.
| Molecular weight | 475.59 |
|---|---|
| Linear formula | C20H38N6O4 · 1/2H2SO4 |
| Assay | ≥90% (HPLC) |
| Solubility | H2O: soluble10 mM (Solutions are stable for a week at 4 °C. Stock solutions are stable up to 6 months at −20 °C.)H2O: soluble50 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Leupeptin hemisulfate salt used for?
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Leupeptin hemisulfate salt is used as a protease inhibitor to prevent protein degradation during biochemical research, particularly during protein extraction and purification.
What is the CAS number and formula for Leupeptin hemisulfate salt?
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The CAS number for Leupeptin hemisulfate salt is 103476-89-7, and its formula is C20H38N6O4 · 1/2H2SO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Leupeptin hemisulfate salt with an assay of ≥90% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Leupeptin hemisulfate salt be handled?
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Handle Leupeptin hemisulfate salt with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Note that it has a WGK Germany rating of 3, indicating it is hazardous to water.
How is Leupeptin hemisulfate salt shipped?
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Leupeptin hemisulfate salt is typically shipped and exported under conditions appropriate for its stability and safety requirements, often requiring refrigerated transport.
How can I request a sample or quote for Leupeptin hemisulfate salt?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or direct contact information, specifying the product name and CAS number.
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