Tri(m-tolyl)phosphine
Tri(m-tolyl)phosphine (CAS: 6224-63-1) is an organophosphorus compound with the linear formula (CH3C6H4)3P and a molecular weight of 304.37 g/mol. This phosphine ligand is valuable in organic synthesis and catalysis. It is widely employed as a ligand in transition metal-catalyzed reactions, particularly in cross-coupling processes, contributing to efficient bond formation.

Catalysis
Serves as a crucial phosphine ligand in various transition metal-catalyzed reactions, facilitating catalytic cycles and enhancing reaction efficiency.
Cross-Coupling Reactions
Effectively utilized in palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings, enabling the formation of carbon-carbon and carbon-heteroatom bonds.
Organic Synthesis
A versatile building block and ligand in complex organic synthesis, aiding in the construction of intricate molecular architectures.
Ligand Development
Employed in the research and development of new catalytic systems and ligands for fine chemical and pharmaceutical intermediate synthesis.
| Molecular weight | 304.37 |
|---|---|
| Linear formula | (CH3C6H4)3P |
| Assay | 98% |
| Melting point | 97-99 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tri(m-tolyl)phosphine used for?
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Tri(m-tolyl)phosphine (CAS: 6224-63-1) is primarily used as a ligand in transition metal-catalyzed reactions, notably in cross-coupling processes and general organic synthesis.
What is the CAS number and chemical formula for Tri(m-tolyl)phosphine?
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The CAS number is 6224-63-1, and the linear formula is (CH3C6H4)3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tri(m-tolyl)phosphine with an assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should Tri(m-tolyl)phosphine be handled safely?
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Tri(m-tolyl)phosphine can cause skin irritation, serious eye irritation, and respiratory irritation (H315-H319-H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves in a well-ventilated area.
How is Tri(m-tolyl)phosphine packed and shipped?
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Tri(m-tolyl)phosphine is carefully packed to ensure integrity during transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Tri(m-tolyl)phosphine?
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To request a sample or a quote for Tri(m-tolyl)phosphine, please contact the Tech Serve Solutions sales team through our website or by phone.
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