L-tert-Leucinol
L-tert-Leucinol (CAS: 112245-13-3) is a chiral amino alcohol with the linear formula (CH3)3CCH(NH2)CH2OH and a molecular weight of 117.19 g/mol. This useful amino acid derivative is employed in various asymmetric reactions within chemical synthesis. Tech Serve Solutions supplies L-tert-Leucinol with an assay of ≥96.0% (sum of enantiomers, GC), suitable for research and development applications.
- IUPAC
- (S)-2-Amino-3,3-dimethyl-1-butanol

Asymmetric Synthesis
L-tert-Leucinol serves as a chiral auxiliary or building block in asymmetric synthesis, facilitating the stereoselective construction of complex molecules. Its structure allows for controlled introduction of chirality in various organic transformations.
Peptide Chemistry
As an amino acid derivative, L-tert-Leucinol finds application in peptide chemistry. It can be incorporated into peptide sequences to modify their properties or used in the synthesis of non-natural peptide analogues.
Chemical Biology Research
This compound is utilised in chemical biology research, potentially as a tool for studying biological processes or as a precursor for synthesising biologically active molecules. Its defined stereochemistry is crucial for specific interactions.
| Molecular weight | 117.19 |
|---|---|
| Linear formula | (CH3)3CCH(NH2)CH2OH |
| Assay | ≥96.0% (sum of enantiomers, GC) |
| Density | 0.9 g/mL at 25 °C(lit.) |
| Optical activity | [α]20/D +38±2°, c = 1.5% in ethanol |
| Application | Useful amino acid employed in various asymmetric reactions.1,2,3 |
| Melting point | 30-34 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 90 °C / 194 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-tert-Leucinol used for?
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L-tert-Leucinol is primarily used as a chiral building block in asymmetric synthesis and peptide chemistry. It is also employed in chemical biology research due to its defined stereochemistry and amino alcohol structure.
What are the CAS number and formula for L-tert-Leucinol?
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The CAS number for L-tert-Leucinol is 112245-13-3. Its linear formula is (CH3)3CCH(NH2)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-tert-Leucinol with an assay of ≥96.0% (sum of enantiomers, GC). This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should L-tert-Leucinol be handled safely?
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L-tert-Leucinol is a warning substance (GHS07) with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes.
How is L-tert-Leucinol packed and shipped?
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L-tert-Leucinol is carefully packed to ensure product integrity during transit. As a global supplier and exporter, Tech Serve Solutions adheres to international shipping regulations for chemical compounds.
How can I request a sample or quote for L-tert-Leucinol?
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To request a sample or a quotation for L-tert-Leucinol, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels, providing your specific requirements.
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