L-α-Cyclopropylglycine
L-α-Cyclopropylglycine (CAS: 49606-99-7, C5H9NO2) is a non-proteinogenic amino acid derivative with a molecular weight of 115.13 g/mol. Characterised by its cyclopropyl side chain, it finds utility as a building block in chemical synthesis and peptide chemistry. It is particularly valuable in the design and construction of unnatural amino acids for applications in chemical biology and medicinal chemistry research.
- IUPAC
- (S)-Amino-cyclopropylacetic acid
Chemical Synthesis
Serves as a versatile chiral building block for the synthesis of complex organic molecules. Its unique cyclopropyl moiety can introduce specific structural and electronic properties into target compounds.
Peptide Chemistry
Incorporated into peptides to create modified structures with altered conformational stability, receptor binding affinity, or metabolic resistance. Useful for developing peptidomimetics and novel peptide-based therapeutics.
Chemical Biology
Utilised in the development of probes and tools for studying biological systems. Its unnatural structure can confer specific properties for bio-imaging or activity-based protein profiling.
Unnatural Amino Acid Research
A key component in the synthesis of non-canonical amino acids for expanding the genetic code or for creating proteins with novel functionalities.
| Molecular weight | 115.13 |
|---|---|
| Empirical formula | C5H9NO2 |
| Assay | 94.0-106.0% (NT)95% |
| Optical activity | [α]/D +101±4°, c = 1% in 1 M HCl |
| Storage temperature | 2-8°C |
| Impurities tested | ≤5.0% water |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-α-Cyclopropylglycine used for?
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L-α-Cyclopropylglycine is used as a building block in chemical synthesis, peptide chemistry, and chemical biology research, particularly for creating unnatural amino acids.
What are the CAS number and formula for L-α-Cyclopropylglycine?
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The CAS number is 49606-99-7, and the empirical formula is C5H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-α-Cyclopropylglycine with an assay of 95%, with impurities of ≤5.0% water. It is supplied as a research-grade chemical and is not intended for USP, BP, or EP use.
How should L-α-Cyclopropylglycine be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is L-α-Cyclopropylglycine a controlled substance?
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The provided data does not indicate that L-α-Cyclopropylglycine is a controlled substance. Its WGK Germany classification is 3.
How is L-α-Cyclopropylglycine packed, shipped, and exported?
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L-α-Cyclopropylglycine is carefully packed for safe transport and is available for export globally by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or a quote for L-α-Cyclopropylglycine?
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Please contact our sales team via the website or email to request a sample or a quotation for L-α-Cyclopropylglycine.
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