L-allo-Threonine
L-allo-Threonine (CAS: 28954-12-3) is a non-proteinogenic amino acid with the molecular formula CH3CH(OH)CH(NH2)CO2H and a molecular weight of 119.12 g/mol. As an unnatural amino acid derivative, it serves as a valuable building block in chemical synthesis and peptide chemistry. Its specific stereochemistry makes it a useful tool in chemical biology research for creating modified peptides and proteins.
- IUPAC
- (2S,3S)-2-Amino-3-hydroxybutyric acid

Chemical Synthesis
L-allo-Threonine is employed as a chiral building block in the synthesis of complex organic molecules. Its unique structure allows for the introduction of specific stereochemical features into target compounds.
Peptide Chemistry
This unnatural amino acid is utilised in the construction of peptides with modified properties. Incorporating L-allo-Threonine can alter peptide conformation, stability, and biological activity.
Chemical Biology Research
Researchers use L-allo-Threonine to probe biological systems and design novel biomolecules. It aids in the study of protein structure-function relationships and the development of peptidomimetics.
Threonine Derivatives
It serves as a precursor or intermediate in the synthesis of various threonine derivatives for specialised chemical applications. Its specific stereoisomer is key for targeted synthetic routes.
| Molecular weight | 119.12 |
|---|---|
| Linear formula | CH3CH(OH)CH(NH2)CO2H |
| Assay | ≥99.0% (TLC) |
| Optical activity | [α]20/D +33±2°, c = 1% in 1 M HCl |
| Melting point | 272 °C (dec.)(lit.)~275 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-allo-Threonine used for?
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L-allo-Threonine is used in chemical synthesis, peptide chemistry, chemical biology research, and as a threonine derivative. It acts as a chiral building block and a tool for creating modified peptides and biomolecules.
What is the CAS number and formula for L-allo-Threonine?
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The CAS number for L-allo-Threonine is 28954-12-3, and its chemical formula is CH3CH(OH)CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-allo-Threonine with a purity of ≥99.0% (TLC). This is a research-grade chemical, and TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
What safety precautions should be taken when handling L-allo-Threonine?
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When handling L-allo-Threonine, it is recommended to use safety equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Handle in a well-ventilated area. The WGK Germany classification is 3.
How is L-allo-Threonine shipped and exported?
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L-allo-Threonine is carefully packed for secure shipment and is available for global export by Tech Serve Solutions, a specialist supplier established in 1998.
How can I request a sample or quote for L-allo-Threonine?
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To request a sample or obtain a quote for L-allo-Threonine, please contact the Tech Serve Solutions sales team through our website or by phone.
Is L-allo-Threonine a controlled substance?
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The provided data does not indicate that L-allo-Threonine (CAS: 28954-12-3) is a controlled substance.
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