L-Valine t-butyl ester hydrochloride
L-Valine t-butyl ester hydrochloride (CAS: 13518-40-6) is a derivative of the essential amino acid L-valine, with the molecular formula C9H19NO2 · HCl and a molecular weight of 209.71 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in peptide chemistry and the development of pharmaceutical intermediates. Its protected nature makes it useful for specific synthetic routes where the free amine or carboxylic acid group needs to be temporarily masked.

Peptide Synthesis
L-Valine t-butyl ester hydrochloride is employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. The tert-butyl ester group shields the carboxylic acid functionality, allowing for controlled peptide chain elongation.
Organic Synthesis Intermediate
This compound acts as a key intermediate in the synthesis of complex organic molecules, including various biologically active compounds and pharmaceutical candidates. Its specific structure facilitates regioselective reactions.
Research and Development
Utilised in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chemical entities. It is a useful reagent for introducing valine residues into target molecules.
| Molecular weight | 209.71 |
|---|---|
| Empirical formula | C9H19NO2 · HCl |
| Assay | ≥99.0% |
| Optical activity | [α]20/D +4.4±1°, c = 2% in H2O |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Valine t-butyl ester hydrochloride used for?
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L-Valine t-butyl ester hydrochloride is primarily used as a protected building block in peptide synthesis and as an intermediate in the broader field of organic synthesis, particularly for creating complex pharmaceutical compounds.
What is the CAS number and formula for L-Valine t-butyl ester hydrochloride?
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The CAS number is 13518-40-6, and its molecular formula is C9H19NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Valine t-butyl ester hydrochloride with an assay of ≥99.0%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should L-Valine t-butyl ester hydrochloride be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection, such as a type N95 (US) or type P1 (EN143) respirator filter, is recommended. The substance has a WGK (German Water Hazard Class) of 3.
Does TSS export L-Valine t-butyl ester hydrochloride?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including L-Valine t-butyl ester hydrochloride.
How can I request a sample or quote for L-Valine t-butyl ester hydrochloride?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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