L-α-Neopentylglycine
L-α-Neopentylglycine (CAS: 57224-50-7; Formula: C7H15NO2; MW: 145.20) is an unnatural amino acid derivative. It finds utility as a building block in chemical synthesis, particularly in the development of novel peptides and in chemical biology research. Its unique structure allows for the introduction of specific steric properties into target molecules, facilitating the study of structure-activity relationships.
- IUPAC
- γ-Methyl-L-leucine,(S)-2-Amino-4,4-dimethylpentanoic acid,L-γ-Methylleucine

Peptide Synthesis
Serves as a non-proteinogenic amino acid for incorporating into peptide chains, enabling the study of modified peptide structures and functionalities.
Chemical Biology Research
Utilised as a tool compound for investigating biological pathways and protein interactions where modified amino acids may play a role.
Drug Discovery
Employed in the design and synthesis of novel therapeutic candidates, leveraging its unique structural features to influence molecular recognition and binding.
Organic Synthesis
Acts as a versatile chiral building block for constructing complex organic molecules with defined stereochemistry.
| Molecular weight | 145.20 |
|---|---|
| Empirical formula | C7H15NO2 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-α-Neopentylglycine primarily used for?
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L-α-Neopentylglycine is primarily used in chemical synthesis, particularly in peptide chemistry and chemical biology, as an unnatural amino acid derivative and chiral building block.
What is the CAS number and chemical formula for L-α-Neopentylglycine?
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The CAS number is 57224-50-7 and the chemical formula is C7H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-α-Neopentylglycine with an assay of ≥98.0% (TLC). This product is not represented as USP, BP, EP, or any pharmacopoeia grade.
What are the safety considerations when handling L-α-Neopentylglycine?
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Handling L-α-Neopentylglycine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK Germany 3, indicating a high hazard to water.
How is L-α-Neopentylglycine packed, shipped, and exported?
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L-α-Neopentylglycine is carefully packed to ensure product integrity during transit. We are experienced global exporters of fine chemicals and laboratory reagents.
How can I request a sample or quote for L-α-Neopentylglycine?
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To request a sample or obtain a quote for L-α-Neopentylglycine, please contact our sales team through the website or by phone.
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