Iodoacetic acid
Iodoacetic acid (CAS: 64-69-7, ICH2CO2H) is a halogenated carboxylic acid with a molecular weight of 185.95 g/mol. This compound is primarily recognised for its utility as a reagent in biochemical research, specifically for the modification of cysteine residues within proteins. Its reactive nature also lends itself to applications in chemical synthesis. Tech Serve Solutions supplies Iodoacetic acid with a high purity, suitable for demanding analytical and synthetic applications.
- Synonyms
- Iodoacetic acid2-Iodoacetic acidMonochloroacetic acid iodo-Acetic acid, iodo-
Protein Modification
Iodoacetic acid is a key reagent for the selective alkylation of cysteine residues in proteins. This modification is crucial for studying protein structure, function, and for preparing proteins for further analysis or enzymatic assays.
Chemical Synthesis
As an organoiodine compound and a carboxylic acid, iodoacetic acid serves as a versatile building block in organic synthesis. It can be used to introduce the carboxymethyl group into various organic molecules.
Biochemical Research
Its ability to irreversibly inhibit enzymes by modifying active-site cysteine residues makes it a valuable tool in understanding enzyme mechanisms and pathways in biological systems.
| Molecular weight | 185.95 |
|---|---|
| Linear formula | ICH2CO2H |
| Assay | ≥98.0% (T) |
| Grade | puriss. p.a. |
| Solubility | H2O: soluble, clear to hazy |
| Storage temperature | 2-8°C |
| Application | Reagent for the modification of cysteine residues in proteins. |
| Melting point | 77-79 °C(lit.)80-84 °C |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2923 6.1(8) / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T,C |
| Risk statements (R) | 25-35 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Iodoacetic Acid used for?
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Iodoacetic acid is primarily used as a reagent for modifying cysteine residues in proteins and in general chemical synthesis.
What are the CAS number and formula for Iodoacetic Acid?
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The CAS number for Iodoacetic Acid is 64-69-7, and its chemical formula is ICH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Iodoacetic Acid with a purity of ≥98.0% (T), specified as puriss. p.a. grade. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should I handle Iodoacetic Acid safely?
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Iodoacetic Acid is a dangerous substance, labelled with GHS05 and GHS06 symbols, and carries the signal word 'Danger'. It is acutely toxic if swallowed (H301) and causes severe skin burns and eye damage (H314). Always use appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, and handle in a well-ventilated area.
Can Tech Serve Solutions export Iodoacetic Acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Iodoacetic Acid, adhering to all necessary regulations.
How can I request a quote or sample for Iodoacetic Acid?
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To request a quote or a sample of Iodoacetic Acid, please contact our sales team directly through the TSS website or by phone.
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