Imino-tris(dimethylamino)phosphorane
Imino-tris(dimethylamino)phosphorane (CAS: 49778-01-0) is a strong, non-ionic, nitrogen-based organic compound with the formula [(CH3)2N]3P=NH and a molecular weight of 178.22 g/mol. It functions as a highly effective base in organic synthesis. This chemical is particularly valuable in reactions requiring a powerful, yet non-nucleophilic, basic catalyst to promote deprotonation and facilitate various chemical transformations.
- IUPAC
- N,N,N′,N′,N″,N″-Hexamethylphosphorimidic triamide,Phosphazene base P1-H
- Synonyms
- N,N,N′,N′,N″,N″-Hexamethylphosphorimidic triamidePhosphazene base P1-H
![Imino-tris(dimethylamino)phosphorane ([(CH3)2N]3P=NH) — chemical structure, CAS 49778-01-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F49778-01-0.png&w=3840&q=75)
Powerful Organic Base
Serves as a potent non-ionic base in organic synthesis, facilitating deprotonation reactions. Its strength makes it suitable for challenging transformations requiring strong basic conditions.
Catalyst in Chemical Synthesis
Employed as a catalyst in various chemical synthesis pathways, promoting reactions by abstracting protons. It is recognized for its utility in facilitating complex organic transformations.
Phosphazene Chemistry
A key member of the phosphazene class of bases, known for their extreme basicity and unique chemical properties. These compounds are explored for advanced synthetic applications.
| Molecular weight | 178.22 |
|---|---|
| Linear formula | [(CH3)2N]3P=NH |
| Assay | 97% |
| Density | 0.979 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.476(lit.) |
| Application | Phosphazene Bases: a Family of Extremely Strong, Non-Ionic, Non-Charged Nitrogen–Bases |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Imino-tris(dimethylamino)phosphorane used for?
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Imino-tris(dimethylamino)phosphorane is used as a strong, non-ionic organic base and catalyst in chemical synthesis, particularly in reactions requiring powerful deprotonation.
What is the CAS number and formula for Imino-tris(dimethylamino)phosphorane?
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The CAS number is 49778-01-0, and its linear formula is [(CH3)2N]3P=NH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Imino-tris(dimethylamino)phosphorane with an assay of 97%. This product is suitable for research and technical applications; TSS does not represent it as USP, BP, or EP grade.
How should I handle Imino-tris(dimethylamino)phosphorane safely?
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This compound is classified as corrosive (H314). Handle with appropriate personal protective equipment, including gloves, goggles, and face shields. Ensure adequate ventilation and use a suitable respirator. Consult the Safety Data Sheet for detailed handling procedures.
Is Imino-tris(dimethylamino)phosphorane regulated as a controlled substance?
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Based on the provided data, there is no indication that Imino-tris(dimethylamino)phosphorane is a controlled substance.
How is Imino-tris(dimethylamino)phosphorane shipped?
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Imino-tris(dimethylamino)phosphorane is shipped under UN 2735, Class 8, Packing Group 3, indicating it is a corrosive material requiring specific transport regulations.
How can I request a quote or sample?
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Please contact the Tech Serve Solutions sales team via our website or direct inquiry channels to request a quote or a sample of Imino-tris(dimethylamino)phosphorane.
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