Methyl 6-fluorochromone-2-carboxylate
Methyl 6-fluorochromone-2-carboxylate (CAS 116543-91-0; C11H7FO4; molar mass 222.17 g/mol) is a fluorinated heterocyclic building block based on the chromone (4H-chromen-4-one) scaffold, bearing a 6-fluoro substituent and a methyl ester at the 2-position. Supplied as a crystalline solid (melting point 137-143 degC), it is used principally in research and pharmaceutical-intermediate synthesis, where the chromone core and reactive ester offer a versatile handle for further functionalisation. Tech Serve Solutions supplies and exports this compound to laboratory and manufacturing customers worldwide.
- IUPAC
- 6-Fluorochromone-2-carboxylic acid methyl ester,Methyl 6-fluoro-4-oxo-4H-chromene-2-carboxylate
- Synonyms
- Methyl 6-fluorochromone-2-carboxylate6-Fluorochromone-2-carboxylic acid methyl esterMethyl 6-fluoro-4-oxo-4H-chromene-2-carboxylateMethyl 6-fluoro-4-oxo-4H-1-benzopyran-2-carboxylate
Pharmaceutical intermediate
Serves as an intermediate and scaffold in the synthesis of chromone-based and benzopyranone-based active molecules. The combination of a fluorine substituent and a hydrolysable methyl ester makes it a convenient point for building more elaborate drug candidates.
Fluorinated building block
Used as a fluorinated heterocyclic building block in medicinal and discovery chemistry. The 6-fluoro group can modulate the electronic character, metabolic stability and binding properties of derived compounds.
Chromone scaffold for derivatisation
The 4-oxo-4H-chromene (chromone) core is a privileged structure across many bioactive families. This ester provides a ready platform for amide coupling, ester exchange, hydrolysis and related transformations.
Research and reference use
Applied in laboratory-scale chemical synthesis and method development. Its defined identity (CAS 116543-91-0) supports use as a characterised reagent in structure-activity and route-scouting studies.
| Molecular weight | 222.17 |
|---|---|
| Empirical formula | C11H7FO4 |
| Melting point | 137-143 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 6-fluorochromone-2-carboxylate used for?
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It is used mainly as a fluorinated heterocyclic building block and pharmaceutical intermediate. The chromone core and reactive 2-methyl ester make it useful for synthesising and derivatising chromone-based molecules in research and manufacturing settings. Specific end-use suitability should be confirmed for your application.
What is the CAS number and molecular formula of Methyl 6-fluorochromone-2-carboxylate?
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Its CAS number is 116543-91-0 and its molecular formula is C11H7FO4 (Hill notation), corresponding to a molecular weight of 222.17 g/mol. It is also known as methyl 6-fluoro-4-oxo-4H-chromene-2-carboxylate.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a technical/research-grade building block, characterised by CAS identity (116543-91-0) and a melting point of 137-143 degC. We do not represent it as a USP, BP or EP pharmacopoeial grade. A current specification or certificate of analysis, including the assay for a given lot, is available on request.
What are the safety and handling considerations?
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Handle as a laboratory chemical using appropriate personal protective equipment and good ventilation, avoiding dust, contact and ingestion. It carries German Water Hazard Class WGK 3 (severely hazardous to water), so prevent release to drains, soil and watercourses and dispose of in line with local regulations. Always consult the current Safety Data Sheet before use; full GHS classification is provided with the SDS.
How is Methyl 6-fluorochromone-2-carboxylate packed, shipped and exported?
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It is packed as a solid in suitable containers sized to order, from gram research quantities to larger amounts, with labelling and documentation for international shipment. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant global delivery with the relevant transport and safety paperwork.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and we will provide availability, a quotation and the current specification or certificate of analysis. Samples can be arranged where appropriate to support your evaluation.
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