N-Boc-3-pyrrolidinone
N-Boc-3-pyrrolidinone (CAS: 101385-93-7), with the molecular formula C9H15NO3 and a molecular weight of 185.22 g/mol, is a key heterocyclic building block. This compound serves as a valuable intermediate in organic synthesis, particularly in studies involving asymmetric hydrogen-transfer bioreduction of ketones. Its controlled storage at 2-8°C ensures stability for research and development applications.
- IUPAC
- N-(tert-Butoxycarbonyl)-3-pyrrolidinone
- Synonyms
- N-(tert-Butoxycarbonyl)-3-pyrrolidinone
Asymmetric Hydrogen-Transfer Bioreduction Studies
N-Boc-3-pyrrolidinone has been utilised in research investigating the asymmetric hydrogen-transfer bioreduction of ketones, specifically employing enzymes like *Leifsonia* alcohol dehydrogenase. This application highlights its utility in stereoselective synthesis and biocatalysis.
Organic Synthesis Intermediate
As a functionalised pyrrolidine derivative, this compound is a versatile building block for the construction of more complex organic molecules. Its Boc protecting group facilitates selective reactions in multi-step synthetic pathways.
Heterocyclic Chemistry Research
The pyrrolidine ring system is prevalent in many biologically active compounds. N-Boc-3-pyrrolidinone serves as a useful starting material or intermediate for synthesizing novel heterocyclic structures with potential pharmacological interest.
| Molecular weight | 185.22 |
|---|---|
| Empirical formula | C9H15NO3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Used in a study of asymmetric hydrogen-transfer bioreduction of ketones with Leifsonia alcohol dehydrogenase.1 |
| Melting point | 34-38 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-3-pyrrolidinone used for?
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N-Boc-3-pyrrolidinone is primarily used as a building block in organic synthesis and has been employed in studies of asymmetric hydrogen-transfer bioreduction of ketones using enzymes such as *Leifsonia* alcohol dehydrogenase.
What are the CAS number and formula for N-Boc-3-pyrrolidinone?
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The CAS number for N-Boc-3-pyrrolidinone is 101385-93-7, and its molecular formula is C9H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-3-pyrrolidinone with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should N-Boc-3-pyrrolidinone be handled and stored?
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N-Boc-3-pyrrolidinone is classified as dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Store in a cool, well-ventilated place at 2-8°C.
How is N-Boc-3-pyrrolidinone packed, shipped, and exported?
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Tech Serve Solutions carefully packs N-Boc-3-pyrrolidinone to ensure safe transit and compliance with international shipping regulations. We are experienced global exporters of fine chemicals and laboratory reagents.
How can I request a sample or quote for N-Boc-3-pyrrolidinone?
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To request a sample or obtain a quotation for N-Boc-3-pyrrolidinone, please contact our sales team through the website or by direct inquiry, providing your specific requirements and shipping details.
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