Methyl 6-fluoropyridine-3-carboxylate
Methyl 6-fluoropyridine-3-carboxylate (CAS 1427-06-1) is a fluorinated pyridine building block with the molecular formula C7H6FNO2 and a molar mass of 155.13 g/mol. Also known as methyl 6-fluoronicotinate, it is a low-melting crystalline solid bearing both a reactive ring fluorine and a methyl ester. Tech Serve Solutions supplies it at 97% assay as a research-grade intermediate for pharmaceutical, agrochemical and fine-chemical synthesis worldwide.
- IUPAC
- Methyl 6-fluoronicotinate
- Synonyms
- Methyl 6-fluoronicotinateMethyl 6-fluoropyridine-3-carboxylate6-Fluoronicotinic acid methyl ester6-Fluoro-3-pyridinecarboxylic acid methyl esterMethyl 6-fluoro-3-pyridinecarboxylate
Pharmaceutical intermediate
Used as a fluorinated heterocyclic building block in medicinal chemistry and the synthesis of pharmaceutical candidates. The activated 2-fluoro position on the pyridine ring is well suited to nucleophilic aromatic substitution.
Fluorinated building block
Serves as a versatile C7 fluoropyridine scaffold for installing fluorine and a substituted-pyridine motif into more complex target molecules during multi-step synthesis.
Ester handle for further functionalisation
The methyl ester is readily hydrolysed, reduced or converted to amides and other carbonyl derivatives, providing a convenient point of elaboration toward nicotinic acid and nicotinamide analogues.
Agrochemical and fine-chemical research
Applied as an intermediate in agrochemical discovery and general fine-chemical synthesis where a fluorinated nicotinate framework is required.
Laboratory reagent
Supplied as a research-grade reagent for use by synthetic, process-development and analytical chemists in laboratory-scale work.
| Molecular weight | 155.13 |
|---|---|
| Empirical formula | C7H6FNO2 |
| Assay | 97% |
| Melting point | 48-52 °C |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 6-fluoropyridine-3-carboxylate used for?
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It is used primarily as a fluorinated pyridine building block and intermediate in pharmaceutical, agrochemical and fine-chemical synthesis. The reactive ring fluorine supports nucleophilic aromatic substitution, while the methyl ester offers a versatile handle for onward functionalisation.
What is the CAS number and molecular formula of Methyl 6-fluoropyridine-3-carboxylate?
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Its CAS number is 1427-06-1 and its molecular formula is C7H6FNO2, with a molecular weight of 155.13 g/mol. It is also known as methyl 6-fluoronicotinate.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 6-fluoropyridine-3-carboxylate at a typical assay of 97% as a research/technical-grade intermediate. We do not represent it as a USP, BP or EP pharmacopoeia grade. A certificate of analysis can be provided with each batch.
What are the safety and handling requirements?
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It is classified under GHS05 and GHS07 with the signal word Danger. The hazard statements are H302 (harmful if swallowed) and H318 (causes serious eye damage). Avoid ingestion and eye contact, wear gloves and eye protection, and handle in a well-ventilated area. Always consult the Safety Data Sheet before use.
How is Methyl 6-fluoropyridine-3-carboxylate packed, shipped and exported?
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It is packed in sealed, labelled containers appropriate to the order quantity, from gram-scale laboratory packs to bulk, each with full documentation. Tech Serve Solutions exports globally in line with applicable transport and customs requirements; packaging and shipping specifics can be confirmed on enquiry.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and a quotation. Samples can be arranged for evaluation where applicable.
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