Fomepizole

CAS 7554-65-6C4H6N2Chemical Synthesis

Fomepizole (CAS 7554-65-6), with the molecular formula C4H6N2 and a molecular weight of 82.10 g/mol, is a pyrazole derivative. This compound is primarily recognised for its critical role as an antidote in cases of methanol and ethylene glycol poisoning. Its ability to inhibit alcohol dehydrogenase enzymes makes it an essential agent in emergency medical treatment protocols for specific toxicological exposures.

IUPAC: 4-Methylpyrazole

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Fomepizole (C4H6N2) — chemical structure, CAS 7554-65-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBuilding BlocksC3 to C5Cell BiologyChemical SynthesisHeterocyclic Building BlocksPyrazoles More...

01 /Applications

Antidote for Poisoning

Fomepizole serves as a vital antidote for methanol and ethylene glycol intoxication. It effectively inhibits the enzyme alcohol dehydrogenase, preventing the formation of toxic metabolites responsible for severe organ damage, particularly in the eyes and kidneys.

Enzyme Inhibition Research

As an inhibitor of alcohol dehydrogenase (ADH), Fomepizole is a valuable tool in biochemical and pharmacological research. Its mechanism of action is studied in relation to ADH enzyme kinetics and its role in alcohol metabolism and toxicity.

Chemical Synthesis

The pyrazole structure of Fomepizole makes it a useful building block in organic synthesis. It can be employed in the development of novel heterocyclic compounds with potential pharmaceutical or agrochemical applications.

02 /Properties

Molecular weight	82.10
Empirical formula	C4H6N2
Assay	99%
Boiling point	99-100 °C/6 mmHg(lit.)
Density	0.993 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.495(lit.)
Solubility	alcohol: soluble(lit.)water: soluble(lit.)
Application	Useful as an antidote in methanol and ethylene glycol poisoning.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	96 °C / 204.8 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

7554-65-6

MDL number

MFCD00005245

PubChem substance

24853343

Beilstein registry

105204

05 /Additional specifications

Gene Information	human ... ADH1A(124), ADH1B(125), ADH1C(126)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Fomepizole used for?

Fomepizole is used as an antidote in methanol and ethylene glycol poisoning. It functions by inhibiting alcohol dehydrogenase.

What is the CAS number and molecular formula for Fomepizole?

The CAS number for Fomepizole is 7554-65-6, and its molecular formula is C4H6N2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fomepizole with a minimum purity of 99%. This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.

How should Fomepizole be handled safely?

Fomepizole is classified with warning signal words and hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Ensure adequate ventilation.

How is Fomepizole packed and shipped?

Fomepizole is carefully packed according to industry standards to ensure safe transport and is available for global export. Please contact us for specific shipping and export inquiries.

How can I request a sample or quote for Fomepizole?

To request a sample or a quotation for Fomepizole, please use the 'Request a Quote' or 'Sample Request' feature on our website or contact our sales department directly.