Formaldehyde neutral buffer solution
Formaldehyde neutral buffer solution (CAS: 50-00-0; linear formula: HCHO; MW: 30.03) is an aqueous solution containing 3.7% formaldehyde and 10-15% methanol as a stabilizer to prevent polymerization. This chemical is widely utilized as a fixative in histology and cell biology for preserving tissue structures. Its buffering capacity helps maintain a stable pH during fixation processes. It is also a key reagent in chemical synthesis as an organic building block.
- IUPAC
- Formaldehyde solution,Formalin
- Synonyms
- Formaldehyde solutionFormalin
Histology and Cell Biology Fixative
Formaldehyde neutral buffer solution is essential for fixing biological tissues and cells, preserving their structure for microscopic examination. It cross-links proteins, preventing degradation and maintaining cellular morphology.
Chemical Synthesis Intermediate
As a source of the formyl group, this solution serves as a versatile building block in organic synthesis. It participates in various reactions, contributing to the construction of more complex organic molecules.
Buffer and Stabilizing Agent
The buffer component helps to maintain a neutral pH, which is crucial for optimal fixation and to prevent undesirable side reactions. The added methanol acts as a stabilizer, inhibiting the polymerization of formaldehyde.
| Molecular weight | 30.03 |
|---|---|
| Linear formula | HCHO |
| Assay | 36.5-38.0% |
| Density | 1.09 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3765 |
| Concentration | 3.7% formaldehyde in H2O |
| Vapour pressure | 52 mmHg (37 °C) |
| Vapour density | 1.03 (vs air) |
| Autoignition temp | 572 °F |
| Contains / stabiliser | 10-15% Methanol as stabilizer (to prevent polymerization) |
| Impurities tested | ≤0.006 meq/g Titr. acid |
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Cation traces | Fe: ≤5 ppmheavy metals (as Pb): ≤5 ppm |
|---|---|
| Anion traces | chloride (Cl-): ≤5 ppmsulfate (SO42-): ≤0.002% |
| Ignition residue | ≤0.005% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Availability | available only in Japan |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Formaldehyde neutral buffer solution used for?
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Formaldehyde neutral buffer solution is primarily used as a fixative in histology and cell biology to preserve biological specimens. It also serves as a building block in chemical synthesis.
What is the CAS number and formula for Formaldehyde neutral buffer solution?
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The CAS number is 50-00-0, and its linear formula is HCHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Formaldehyde neutral buffer solution with an assay of 36.5-38.0% formaldehyde. We do not represent this product as USP, BP, or EP grade.
How should Formaldehyde neutral buffer solution be handled safely?
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Handle with appropriate personal protective equipment (PPE) as indicated by precautionary statement P280. It is important to work in a well-ventilated area due to formaldehyde's hazardous nature.
Is Formaldehyde neutral buffer solution a controlled substance?
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The provided data does not indicate that Formaldehyde neutral buffer solution is a controlled substance.
How is Formaldehyde neutral buffer solution packed and shipped?
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Formaldehyde neutral buffer solution is available only in Japan. Shipping and packing details are handled according to regulatory standards.
How can I request a quote or sample?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or listed contact information.
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