Fluoroacetamide
Fluoroacetamide (CAS: 640-19-7; FCH₂CONH₂) is a fluorinated organic compound with a molecular weight of 77.06. This chemical serves as a valuable building block in organic synthesis, primarily involved in C-N coupling reactions to form amides and nitrogen-containing heterocycles. It also finds application in the substitution of aryl triflates. Fluoroacetamide is utilised in analytical chemistry, specifically in mass spectrometry databases for pesticide residue screening.
- IUPAC
- NSC 31876

C-N Coupling Reactions
Fluoroacetamide acts as a reactant in C-N coupling reactions, facilitating the formation of amides and various nitrogen-containing heterocyclic compounds. This makes it a useful intermediate in synthetic organic chemistry.
Substitution in Aryl Triflates
This compound is employed in nucleophilic substitution reactions involving aryl triflates. It enables the introduction of the fluoroacetamide moiety into complex molecular structures.
Analytical Standard for Pesticide Screening
Fluoroacetamide is incorporated into mass spectrometry databases. It serves as a reference standard for the rapid detection and quantification of pesticide residues using fast liquid chromatography coupled with time-of-flight mass spectrometry (LC-TOF-MS).
| Molecular weight | 77.06 |
|---|---|
| Linear formula | FCH2CONH2 |
| Application | Reactant involved in:• C-N coupling to amides and nitrogen-containing heterocycles1• Substitution in aryl triflates2Used in mass databases for screening of pesticide residues via fast liquid chromatography TOF mass spectrometry3 |
| Melting point | 106-108 °C(lit.) |

Hazard statements
- H300Fatal if swallowed
- H311Toxic in contact with skin
Precautionary statements
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 24-28 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fluoroacetamide used for?
+
Fluoroacetamide (CAS: 640-19-7) is primarily used as a building block in organic synthesis for C-N coupling reactions and substitution in aryl triflates. It is also used in mass spectrometry for pesticide residue screening.
What are the CAS number and formula for Fluoroacetamide?
+
The CAS number for Fluoroacetamide is 640-19-7, and its linear formula is FCH₂CONH₂.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Fluoroacetamide as a research chemical. We do not represent it as USP, BP, or EP grade. Please refer to the product's Certificate of Analysis for specific purity details.
How should Fluoroacetamide be handled safely?
+
Fluoroacetamide is classified as Danger (GHS06) and is acutely toxic (H300, H311). Strict adherence to safety protocols is essential. Recommended personal protective equipment includes eyeshields, face shields, appropriate gloves, and respiratory protection (e.g., a full-face particle respirator type N100 or equivalent). Handle only in a well-ventilated area or under a fume hood.
Is Fluoroacetamide a controlled substance?
+
The provided data does not indicate that Fluoroacetamide is a controlled substance. However, regulations can vary by region, and customers should verify local compliance requirements.
How is Fluoroacetamide packed, shipped, and exported?
+
Fluoroacetamide is packed and shipped according to international regulations for hazardous materials (UN 2811 6.1 / PGII). As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, ensuring compliance with all relevant shipping and customs requirements.
How can I request a sample or quote for Fluoroacetamide?
+
To request a sample or a quote for Fluoroacetamide, please use the 'Request a Quote' or 'Sample Request' function on our website, or contact our sales department directly with your inquiry, referencing the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis