Fluoro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
Fluoro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate (CAS 164298-23-1) is a chemical compound with the linear formula [FC[=N(CH3)2]N(CH3)2]PF6 and a molecular weight of 264.12 g/mol. This reagent is primarily utilised in chemical synthesis, particularly in peptide chemistry and fluorination reactions. Its applications extend to the development of novel therapeutic agents and complex organic molecules.
- IUPAC
- TFFH
- Synonyms
- N′-tetramethylformamidinium hexafluorophosphate164298-23-1[FC[=N(CH3)2]N(CH3)2]PF6
Synthesis of Antimicrobial Agents
This compound serves as a reagent in the synthesis of cationic antimicrobial beta-amino acid derivatives and small beta-peptidomimetics. These molecules are explored for their potential as novel antimicrobial therapies.
Development of Neurological Therapeutics
It is employed in the synthesis of amine prodrugs for selective neuronal nitric oxide synthase inhibitors, contributing to research in neurological disorders. Additionally, it facilitates the creation of Philanthotoxin analogues for ionotropic glutamate receptor inhibition.
Advanced Material and Nanoparticle Assembly
The reagent is utilised in selective synthesis pathways, such as for cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors. It also plays a role in hydrazone ligation for the assembly of multifunctional viral nanoparticles.
| Molecular weight | 264.12 |
|---|---|
| Linear formula | [FC[=N(CH3)2]N(CH3)2]PF6 |
| Assay | 97% |
| Application | Reagent for synthesis of: Cationic antimicrobial β-2,2-amino acid derivatives1 Philanthotoxin analogues for inhibition of the ionotropic glutamate receptor2 Small β-peptidomimetics for antimicrobials3 Amine prodrugs of selective neuronal nitric oxide synthase inhibitors4Reagent for: Selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors5 Hydrazone ligation to assemble multifunctional viral nanoparticles6 |
| Melting point | 104-109 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fluoro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate used for?
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Fluoro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate is a reagent utilised in various synthetic applications, including the synthesis of antimicrobial agents, neurological therapeutics, and in the assembly of advanced materials and viral nanoparticles.
What are the CAS number and molecular formula?
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The CAS number is 164298-23-1 and the linear formula is [FC[=N(CH3)2]N(CH3)2]PF6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. As this is not a pharmacopoeia grade, TSS does not represent it as USP, BP, or EP.
How should Fluoro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate be handled?
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This compound is a Warning substance with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with a dust mask type N95 (US), eyeshields, and gloves in a well-ventilated area. Follow precautionary statements P261 and P305 + P351 + P338.
How is this chemical packed and exported?
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Tech Serve Solutions packs and exports this chemical with appropriate safety and regulatory compliance for global distribution.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team via the website or direct contact details provided.
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