Fluorobenzene

CAS 462-06-6C6H5FChemical Synthesis

Fluorobenzene (CAS: 462-06-6; C6H5F) is a clear, colourless liquid with a molecular weight of 96.10 g/mol. This organofluorine compound serves as a valuable building block in organic synthesis. Its primary applications lie in the pharmaceutical and agrochemical industries, where it is used as an intermediate in the production of more complex molecules. Fluorobenzene is also employed in specialised chemical research.

Synonyms: Phenyl fluorideFluobenzene

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Fluorobenzene (C6H5F) — chemical structure, CAS 462-06-6; Chemistry, fine chemical supplied by Tech Serve Solutions

ArylBuilding BlocksChemical SynthesisFluorinated Building BlocksHalogenated HydrocarbonsOrganic Building Blocks

01 /Applications

Pharmaceutical Intermediate

Fluorobenzene is a key precursor in the synthesis of various active pharmaceutical ingredients (APIs). Its fluorinated structure can impart desirable properties to drug molecules, influencing lipophilicity and metabolic stability.

Agrochemical Synthesis

This compound is utilised in the development of novel agrochemicals, including herbicides and pesticides. The incorporation of fluorine can enhance the efficacy and persistence of these agricultural products.

Organic Synthesis Building Block

As a versatile aryl fluorinated building block, fluorobenzene is employed in diverse organic reactions. It enables the introduction of a phenyl ring with a fluorine substituent into various molecular scaffolds.

Specialty Chemical Research

Fluorobenzene finds application in academic and industrial research settings for exploring new chemical transformations and developing innovative materials. Its reactivity profile makes it a useful reagent in complex synthetic routes.

02 /Properties

Molecular weight	96.10
Empirical formula	C6H5F
Assay	≥97.0% (GC)
Boiling point	85 °C(lit.)
Density	1.024 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.465(lit.)n20/D 1.465
Melting point	−42 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Danger

Hazard statements

H225Highly flammable liquid and vapour
H319Causes serious eye irritation
H412Harmful to aquatic life with long-lasting effects

Precautionary statements

P210Keep away from heat, sparks and open flames. No smoking
P273Avoid release to the environment
P305IF IN EYES

Protective equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	-15 °C / 5 °F
Transport (UN / ADR)	UN 2387 3 / PGII
Water hazard class (WGK, DE)	2
Hazard codes (EU)	F,Xi
Risk statements (R)	11-36-52/53
Safety statements (S)	16-26-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

462-06-6

MDL number

MFCD00000280

PubChem substance

24894898

Beilstein registry

1236623

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fluorobenzene used for?

Fluorobenzene (CAS: 462-06-6, Formula: C6H5F) is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and as a general building block in organic chemical research.

What is the CAS number and formula for Fluorobenzene?

The CAS number for Fluorobenzene is 462-06-6, and its chemical formula is C6H5F.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fluorobenzene with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.

How should Fluorobenzene be handled safely?

Fluorobenzene is a highly flammable liquid and vapour (H225) and causes serious eye irritation (H319). It is also harmful to aquatic life with long-lasting effects (H412). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area away from ignition sources.

How is Fluorobenzene packed and shipped?

Fluorobenzene is shipped as a regulated material (UN 2387, Class 3, Packing Group II). TSS exports globally, adhering to all relevant shipping and safety regulations for hazardous chemicals.

How can I request a sample or quote for Fluorobenzene?

To request a sample or a quote for Fluorobenzene, please contact our sales team via the website or by phone, providing your specific requirements and shipping details.