3,5-Dimethoxybenzylmagnesium chloride solution
3,5-Dimethoxybenzylmagnesium chloride solution (CAS: 135808-66-1, C6H3(OCH3)2CH2MgCl, MW: 210.94) is an organometallic reagent supplied as a 0.2 M solution in THF. It is a reactive Grignard reagent used primarily in organic synthesis for introducing the 3,5-dimethoxybenzyl group. Its applications span the construction of complex molecules within chemical research and development.
- Synonyms
- C6H3(OCH3)2CH2MgCl
Organometallic Synthesis
As a Grignard reagent, it is instrumental in forming new carbon-carbon bonds by reacting with electrophiles such as aldehydes, ketones, and esters. This facilitates the synthesis of complex organic structures.
Building Block for Pharmaceuticals
The 3,5-dimethoxybenzyl moiety can be incorporated into potential pharmaceutical intermediates and drug candidates. Its reactivity allows for its use in multi-step synthetic routes towards biologically active compounds.
Research and Development
This compound serves as a valuable tool in academic and industrial research laboratories for exploring novel synthetic methodologies and preparing target molecules.
| Molecular weight | 210.94 |
|---|---|
| Linear formula | C6H3(OCH3)2CH2MgCl |
| Boiling point | 65-67 °C |
| Density | 0.913 g/mL at 25 °C |
| Concentration | 0.2 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Dimethoxybenzylmagnesium chloride solution used for?
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3,5-Dimethoxybenzylmagnesium chloride solution (CAS: 135808-66-1) is used as a Grignard reagent in organic synthesis for introducing the 3,5-dimethoxybenzyl group into molecules, particularly in the development of complex organic compounds and potential pharmaceutical intermediates.
What is the CAS number and chemical formula?
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The CAS number is 135808-66-1 and the linear chemical formula is C6H3(OCH3)2CH2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Dimethoxybenzylmagnesium chloride solution at a concentration of 0.2 M in THF. This product is intended for laboratory research and development purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should 3,5-Dimethoxybenzylmagnesium chloride solution be handled?
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This compound is a Danger hazard. It is flammable (Flash Point -17 °C), reacts violently with water, can cause severe skin burns and eye damage, and may cause respiratory irritation. It may also form explosive peroxides. Handle with extreme caution under an inert atmosphere, avoiding contact with water, air, ignition sources, and incompatible materials. Refer to the Safety Data Sheet for full details.
Is 3,5-Dimethoxybenzylmagnesium chloride solution shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,5-Dimethoxybenzylmagnesium chloride solution.
How can I request a quote or sample?
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To request a quote or sample of 3,5-Dimethoxybenzylmagnesium chloride solution, please contact our sales team through the website or by phone.
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