Isobutanesulfonyl chloride
Isobutanesulfonyl chloride (CAS: 35432-36-1), with the empirical formula C4H9ClO2S and a molecular weight of 156.63 g/mol, is a reactive sulfonyl halide. It serves as a versatile building block in organic synthesis, particularly for introducing the isobutanesulfonyl group into various molecular structures. This compound is essential for researchers and chemists engaged in the development of novel organic compounds and pharmaceutical intermediates.
- IUPAC
- 2-Methyl-1-propylsulfonyl chloride
- Synonyms
- 2-Methyl-1-propylsulfonyl chloride

Organic Synthesis Intermediate
Isobutanesulfonyl chloride is widely employed as a key intermediate in the synthesis of complex organic molecules. It facilitates the introduction of the sulfonyl moiety, which can be crucial for modifying the properties of target compounds.
Pharmaceutical Research
This chemical acts as a valuable building block in medicinal chemistry for the development of new therapeutic agents. Its reactivity allows for the creation of diverse molecular scaffolds relevant to drug discovery programmes.
Specialty Chemical Production
It is utilized in the production of specialty chemicals where the isobutanesulfonyl group imparts specific functional characteristics. This includes its use in the synthesis of various sulfur-containing organic compounds.
| Molecular weight | 156.63 |
|---|---|
| Empirical formula | C4H9ClO2S |
| Assay | 97% |
| Density | 1.200 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.454(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 88 °C / 190.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isobutanesulfonyl chloride used for?
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Isobutanesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and specialty chemical production for introducing the isobutanesulfonyl group.
What are the CAS number and formula for Isobutanesulfonyl chloride?
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The CAS number for Isobutanesulfonyl chloride is 35432-36-1, and its empirical formula is C4H9ClO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isobutanesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the main safety concerns when handling Isobutanesulfonyl chloride?
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Isobutanesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including full-face shields, gloves, and suitable respiratory protection, must be used.
How is Isobutanesulfonyl chloride shipped and exported?
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Isobutanesulfonyl chloride is shipped as a hazardous material under UN 3265, Class 8, Packing Group II.
How can I request a sample or quote for Isobutanesulfonyl chloride?
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To request a sample or a quote for Isobutanesulfonyl chloride, please contact our sales team through the website or by phone.
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