3,5-Dimethoxybenzyl bromide
3,5-Dimethoxybenzyl bromide (CAS 877-88-3) is an organic compound with the linear formula (CH3O)2C6H3CH2Br and a molecular weight of 231.09 g/mol. As a versatile building block, it finds utility in organic synthesis, particularly in the preparation of complex molecules. Its structure, featuring a benzyl bromide moiety and two methoxy groups, makes it a valuable intermediate for introducing the 3,5-dimethoxybenzyl group into various chemical structures.
- Synonyms
- (CH3O)2C6H3CH2Br

Organic Synthesis Intermediate
3,5-Dimethoxybenzyl bromide serves as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Its reactive benzyl bromide group allows for facile nucleophilic substitution reactions, enabling the formation of new carbon-carbon or carbon-heteroatom bonds.
Pharmaceutical Research
This compound is employed in research and development for the synthesis of novel drug candidates. The 3,5-dimethoxybenzyl moiety can be incorporated into molecules to modulate their pharmacological properties, such as solubility, metabolic stability, or receptor binding affinity.
Materials Science
It can be utilized in the development of new materials with specific electronic or optical properties. The dimethoxybenzyl unit can be integrated into polymers or organic frameworks to tune their characteristics.
| Molecular weight | 231.09 |
|---|---|
| Linear formula | (CH3O)2C6H3CH2Br |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Melting point | 69-70 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Dimethoxybenzyl bromide used for?
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3,5-Dimethoxybenzyl bromide is primarily used as a building block and intermediate in organic synthesis, including pharmaceutical research and materials science.
What is the CAS number and chemical formula for 3,5-Dimethoxybenzyl bromide?
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The CAS number is 877-88-3, and the linear formula is (CH3O)2C6H3CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Dimethoxybenzyl bromide with a minimum assay of 95%. We do not represent this product as meeting any pharmacopoeia standards (USP, BP, EP) unless explicitly stated in the specifications.
How should 3,5-Dimethoxybenzyl bromide be handled safely?
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This compound is classified as Danger (GHS05) and can cause severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Store at 2-8°C.
How is 3,5-Dimethoxybenzyl bromide shipped and exported?
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3,5-Dimethoxybenzyl bromide is shipped and exported in compliance with all relevant regulations for hazardous materials, labelled as UN 3261, Class 8, Packing Group II.
How can I request a sample or quote for 3,5-Dimethoxybenzyl bromide?
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To request a sample or obtain a quote, please contact our sales department through the website or by phone, providing your contact details and the quantity required.
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