Tech Serve Solutions

1,4-Phenylene diisocyanate

CAS 104-49-4C6H4(NCO)2Chemical Synthesis

1,4-Phenylene diisocyanate (CAS 104-49-4), molecular formula C6H4(NCO)2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

1,4-Phenylene diisocyanate
Building BlocksChemical SynthesisIsocyanatesNitrogen CompoundsOrganic Building Blocks
01 /Properties
Molecular weight160.13
Linear formulaC6H4(NCO)2
Boiling point260 °C(lit.)
SolubilityTHF: solubleacetone: solubleethyl acetate: solubletoluene: soluble
Vapour pressure<0.01 mmHg (20 °C)
Application1,4-Phenylene diisocyanate has been used:• as croos-linking reagent to investigate the mechanism of enzyme immobilization on silanized surfaces1• in the synthesis of dipodal bis-urea receptor, a selective receptor for hydrogen sulfate2• in deposition of polyurea resists films via molecular layer deposition3
Melting point96-99 °C(lit.)
02 /Safety & handling
Corrosive
Corrosive
Harmful / irritant
Harmful / irritant
Health hazard
Health hazard
Danger

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H334May cause allergy or asthma symptoms if inhaled

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P342
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Flash point>113 °C / >235.4 °F
Transport (UN / ADR)UN 3335
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)20/21/22-38-41-42
Safety statements (S)22-26-36/37-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
104-49-4
MDL number
MFCD00002025
PubChem substance
24855867
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 1,4-Phenylene diisocyanate?

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1,4-Phenylene diisocyanate (CAS 104-49-4), molecular formula C6H4(NCO)2, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of 1,4-Phenylene diisocyanate does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1,4-Phenylene diisocyanate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of 1,4-Phenylene diisocyanate?

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1,4-Phenylene diisocyanate has CAS number 104-49-4 and molecular formula C6H4(NCO)2. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for 1,4-Phenylene diisocyanate?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of 1,4-Phenylene diisocyanate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should 1,4-Phenylene diisocyanate be stored?

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Store 1,4-Phenylene diisocyanate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is 1,4-Phenylene diisocyanate used for?

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1,4-Phenylene diisocyanate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for 1,4-Phenylene diisocyanate?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need 1,4-Phenylene diisocyanate in a specific grade or volume?

Request a quote