Ethyl N-Boc-piperidine-3-carboxylate
Ethyl N-Boc-piperidine-3-carboxylate (CAS: 130250-54-3, Formula: C13H23NO4) is a key heterocyclic building block for advanced organic synthesis. With a molecular weight of 257.33 g/mol, this compound serves as a versatile reactant in the creation of various complex molecules. Its applications span the development of pharmaceutical intermediates, including GABAA receptor agonists and selective TACE inhibitors, making it invaluable for research and development in the life sciences.
- IUPAC
- 1-(tert-Butoxycarbonyl)-piperidine-3-carboxylic acid ethyl ester,1-(tert-Butyl) 3-ethyl 1,3-piperidinedicarboxylate,N-Boc-DL-nipecotic acid ethyl ester,Ethyl N-Boc-DL-nipecotate
- Synonyms
- 1-(tert-Butoxycarbonyl)-piperidine-3-carboxylic acid ethyl ester1-(tert-Butyl) 3-ethyl 1,3-piperidinedicarboxylateN-Boc-DL-nipecotic acid ethyl esterEthyl N-Boc-DL-nipecotate
Synthesis of GABAA Receptor Agonists
Ethyl N-Boc-piperidine-3-carboxylate is utilised as a reactant in the synthesis pathways leading to GABAA receptor agonists, which are compounds of interest in neurological research.
Preparation of Piperidine Derivatives
This compound functions as a precursor for a range of piperidine derivatives, enabling the construction of diverse molecular scaffolds essential for medicinal chemistry.
Development of Selective TACE Inhibitors
It serves as a building block in the synthetic route for selective TACE (Tumor Necrosis Factor-alpha Converting Enzyme) inhibitors, which are investigated for their therapeutic potential.
Creation of HDL-Elevating Agents
The molecule is employed in the synthesis of agents designed to elevate High-Density Lipoprotein (HDL) levels, contributing to research in cardiovascular health.
Synthesis of α-Sulfonyl Hydroxamic Acid Derivatives
This intermediate is used in the preparation of α-sulfonyl hydroxamic acid derivatives, a class of compounds with diverse biological activities.
Iboga-Alkaloid Family Chemicals
Ethyl N-Boc-piperidine-3-carboxylate is a useful synthon for constructing chemicals belonging to the Iboga-alkaloid family, known for their complex structures.
| Molecular weight | 257.33 |
|---|---|
| Empirical formula | C13H23NO4 |
| Assay | ≥97.0% (GC)≥97.0% |
| Application | Reactant for synthesis of:• GABAA receptor agonists1• Piperidine derivatives2• Selective TACE inhibitors3• HDL-elevating agents4• α-Sulfonyl hydroxamic acid derivatives5• chemicals in the Iboga-alkaloid family6 |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43-52 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl N-Boc-piperidine-3-carboxylate used for?
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It is primarily used as a reactant in organic synthesis for creating various chemical entities, including GABAA receptor agonists, piperidine derivatives, selective TACE inhibitors, HDL-elevating agents, α-sulfonyl hydroxamic acid derivatives, and chemicals within the Iboga-alkaloid family.
What are the CAS number and formula for Ethyl N-Boc-piperidine-3-carboxylate?
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The CAS number is 130250-54-3, and the empirical formula is C13H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl N-Boc-piperidine-3-carboxylate with an assay of ≥97.0% (GC) or ≥97.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety concerns when handling this chemical?
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This compound is classified as a Warning. It is harmful if swallowed (H302), may cause an allergic skin reaction (H317), and causes serious eye irritation (H319). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used.
Is Ethyl N-Boc-piperidine-3-carboxylate suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Ethyl N-Boc-piperidine-3-carboxylate. We adhere to all necessary shipping and handling regulations for international distribution.
How can I request a sample or quote for Ethyl N-Boc-piperidine-3-carboxylate?
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To request a sample or a quote, please visit the 'Contact Us' section of the Tech Serve Solutions website or contact our sales department directly with your requirements.
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