Ethyl N-Boc-oxamidate
Ethyl N-Boc-oxamidate (CAS: 216959-34-1, Formula: C9H15NO5, Molar Mass: 217.22 g/mol) is a valuable organic compound utilised in chemical synthesis. Its primary function is as a protecting group reagent, particularly for amines in peptide chemistry and related fields. This compound facilitates complex molecular construction by temporarily masking reactive amine functionalities, enabling selective reactions elsewhere in the molecule.

Amine Protection
Ethyl N-Boc-oxamidate serves as a reagent for the introduction of the tert-butyloxycarbonyl (Boc) protecting group onto amine functionalities. This protection strategy is crucial in multi-step organic synthesis, particularly in peptide synthesis, to prevent unwanted side reactions.
Peptide Synthesis
In the field of peptide chemistry, this compound is employed to protect amino groups of amino acids. The Boc group's lability under mild acidic conditions allows for its selective removal without damaging the growing peptide chain.
Chemical Synthesis Reagent
Beyond peptide applications, Ethyl N-Boc-oxamidate is a versatile reagent in general organic synthesis. It enables chemists to control reactivity and achieve regioselectivity or chemoselectivity in complex molecular assemblies.
Chemical Biology Research
Researchers in chemical biology may utilise this reagent for the synthesis of modified biomolecules or probes where amine protection is a necessary step in the synthetic route.
| Molecular weight | 217.22 |
|---|---|
| Empirical formula | C9H15NO5 |
| Assay | ≥97.0% |
| Refractive index | n20/D 1.449 |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl N-Boc-oxamidate used for?
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Ethyl N-Boc-oxamidate is primarily used as a reagent for introducing the tert-butyloxycarbonyl (Boc) protecting group onto amine functionalities in organic synthesis, especially in peptide chemistry.
What are the CAS number and formula for Ethyl N-Boc-oxamidate?
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The CAS number for Ethyl N-Boc-oxamidate is 216959-34-1, and its empirical formula is C9H15NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl N-Boc-oxamidate with a minimum purity of ≥97.0%. This product is intended for research and technical use. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Ethyl N-Boc-oxamidate be handled safely?
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Ethyl N-Boc-oxamidate is classified with the GHS07 symbol and a Warning signal word. It carries the hazard statement H302, indicating it is harmful if swallowed. Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used when handling. Store at -20°C.
Does Tech Serve Solutions export Ethyl N-Boc-oxamidate?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Ethyl N-Boc-oxamidate, and can fulfil export orders worldwide.
How can I request a quote or sample for Ethyl N-Boc-oxamidate?
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To request a quote or a sample of Ethyl N-Boc-oxamidate, please contact our sales team through the website or by telephone. Please reference the product name and CAS number (216959-34-1) in your inquiry.
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