Ethyl bromofluoroacetate
Ethyl bromofluoroacetate (CAS 401-55-8) is a fluorinated organic building block with the linear formula BrCH(F)CO₂C₂H₅ and a molar mass of 184.99 g/mol. This ester is a valuable intermediate in organic synthesis, particularly for the preparation of complex fluorinated compounds. Its reactivity makes it suitable for introducing fluorinated moieties into various molecular structures, finding utility in the development of novel pharmaceuticals and agrochemicals.
Synthesis of Polyfluoroalkyl-Substituted Fluoro Enol Ethers
Ethyl bromofluoroacetate serves as a key intermediate in the synthesis of polyfluoroalkyl-substituted fluoro enol ethers. These compounds are important in materials science and specialty chemical applications.
Preparation of N-Protected α-Fluoroglycines
This reagent is utilized in the preparation of N-protected α-fluoroglycines. These fluorinated amino acid derivatives are significant in medicinal chemistry and peptide research.
Organic Synthesis Building Block
As a versatile fluorinated building block, it is employed in various organic synthesis pathways for introducing fluorine atoms or fluorinated fragments into target molecules, supporting drug discovery and development.
| Molecular weight | 184.99 |
|---|---|
| Linear formula | BrCH(F)CO2C2H5 |
| Assay | 97% |
| Boiling point | 154 °C(lit.) |
| Density | 1.565 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.424(lit.) |
| Storage temperature | 2-8°C |
| Application | An intermediate useful for the synthesis of polyfluoroalkyl-substituted fluoro enol ethers1 and N-protected α-fluoroglycines.2 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl bromofluoroacetate used for?
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Ethyl bromofluoroacetate is primarily used as an intermediate in organic synthesis for the preparation of polyfluoroalkyl-substituted fluoro enol ethers and N-protected α-fluoroglycines. It also functions as a general fluorinated building block in chemical synthesis.
What is the CAS number and formula for Ethyl bromofluoroacetate?
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The CAS number is 401-55-8, and its linear formula is BrCH(F)CO₂C₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl bromofluoroacetate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Ethyl bromofluoroacetate?
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Ethyl bromofluoroacetate is classified with GHS07 symbol and a 'Warning' signal word. It carries hazard statements H302, H312, H315, H319, H332, and H335, indicating it is harmful if swallowed, in contact with skin, and if inhaled, and causes skin and serious eye irritation. It is also harmful to the respiratory tract. Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Store at 2-8°C.
How is Ethyl bromofluoroacetate packed, shipped, and exported?
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Ethyl bromofluoroacetate is carefully packed according to relevant regulations for chemical transport. Tech Serve Solutions is a global supplier and exporter, equipped to handle international shipments.
How can I request a quote or sample for Ethyl bromofluoroacetate?
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To request a quote or sample, please contact our sales department via the website or by phone, providing your contact details and the quantity required.
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