Ethyl bromopyruvate
Ethyl bromopyruvate (CAS: 70-23-5), with the linear formula BrCH₂COCOOC₂H₅ and a molecular weight of 195.01 g/mol, is a versatile organic compound. It functions as a key building block in chemical synthesis, particularly for creating complex organic molecules. Its applications include the preparation of various heterocyclic compounds and specialized esters. It is utilized in research and development settings for synthetic organic chemistry, contributing to the creation of novel chemical entities.
Synthesis of Heterocyclic Compounds
Ethyl bromopyruvate serves as a crucial starting material in the synthesis of derivatives of imidazo[1,2-b]pyridazine-2-carboxylic acids, esters, and amides. This highlights its utility in constructing nitrogen-containing heterocyclic ring systems.
Preparation of Sulfoenolpyruvate
The compound is employed as a reagent in the synthesis of sulfoenolpyruvate, a valuable intermediate in biochemical and synthetic pathways. This application underscores its role in specialized organic synthesis.
One-Pot Synthesis of Thiazole Derivatives
Ethyl bromopyruvate is utilized in a one-pot synthesis to yield ethyl 2-(4-aryl-2-dialkylamino-1,3-thiazole-5-yl)-2-oxoacetates. This demonstrates its efficiency in creating complex thiazole structures in a streamlined process.
| Molecular weight | 195.01 |
|---|---|
| Linear formula | BrCH2COCOOC2H5 |
| Assay | 90% |
| Grade | technical |
| Boiling point | 98-100 °C/10 mmHg(lit.) |
| Density | 1.554 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.469(lit.) |
| Storage temperature | 2-8°C |
| Application | Ethyl bromopyruvate was used in the synthesis of derivatives of imidazo[1,2-b]pyridazine-2-carboxylic acids, esters and amides1. It was used as starting reagent in the synthesis of sulfoenolpyruvate2. It was used in one-pot synthesis of ethyl 2-(4-aryl-2-dialkylamino-1,3-thiazole-5-yl)-2-oxoacetates3. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl bromopyruvate used for?
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Ethyl bromopyruvate is used as a building block in chemical synthesis, for example, in the preparation of imidazo[1,2-b]pyridazine derivatives, sulfoenolpyruvate, and ethyl 2-(4-aryl-2-dialkylamino-1,3-thiazole-5-yl)-2-oxoacetates.
What are the CAS number and formula for Ethyl bromopyruvate?
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The CAS number for Ethyl bromopyruvate is 70-23-5, and its linear formula is BrCH₂COCOOC₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl bromopyruvate with a technical grade and an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Ethyl bromopyruvate be handled safely?
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Ethyl bromopyruvate is a Warning substance classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Ensure adequate ventilation or use a suitable respirator. Store at 2-8°C.
How is Ethyl bromopyruvate packed and shipped?
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Ethyl bromopyruvate is typically packed in suitable containers for chemical transport. Tech Serve Solutions exports fine chemicals and laboratory reagents globally, adhering to all necessary shipping regulations.
How can I request a quote or sample of Ethyl bromopyruvate?
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To request a quote or a sample of Ethyl bromopyruvate, please contact our sales team through the website or by phone. We will be happy to assist you with your requirements.
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