Di-tert-butyl hydrazodiformate
Di-tert-butyl hydrazodiformate (CAS: 16466-61-8) is an organic compound with the linear formula [NHCO2C(CH3)3]2 and a molecular weight of 232.28 g/mol. It is primarily utilised as a building block and reagent in organic synthesis. This compound finds application in the preparation of complex molecules, including pharmaceutical intermediates, and in various catalysed reactions. Tech Serve Solutions supplies this chemical for research and development purposes.
- IUPAC
- tert-Butyl hydrazodiformate
![Di-tert-butyl hydrazodiformate ([NHCO2C(CH3)3]2) — chemical structure, CAS 16466-61-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F16466-61-8.png&w=3840&q=75)
Synthesis of Aminobicyclopyrazolone Hydrochloride
Di-tert-butyl hydrazodiformate served as a key starting reagent in a multi-step synthesis pathway leading to the formation of aminobicyclopyrazolone hydrochloride.
Pd-Catalyzed Amination Reactions
This compound has been employed as a reagent in palladium-catalyzed amination processes involving halo-pyridine substrates, facilitating the formation of C-N bonds.
Organic Synthesis Building Block
As a versatile building block, di-tert-butyl hydrazodiformate is valuable in constructing more complex organic molecules for various chemical research applications.
| Molecular weight | 232.28 |
|---|---|
| Linear formula | [NHCO2C(CH3)3]2 |
| Assay | 97% |
| Application | Di-tert-butyl hydrazodiformate was used as starting reagent during the four-step synthesis of the aminobicyclopyrazolone hydrochloride1. It was used as reagent during Pd-catalyzed amination reactions of halo-pyridine substrates2. |
| Melting point | 123-126 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Di-tert-butyl hydrazodiformate used for?
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Di-tert-butyl hydrazodiformate is used as a starting reagent in multi-step syntheses, such as for aminobicyclopyrazolone hydrochloride, and as a reagent in Pd-catalyzed amination reactions of halo-pyridine substrates. It also serves as a general building block in organic synthesis.
What are the CAS number and formula for Di-tert-butyl hydrazodiformate?
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The CAS number for Di-tert-butyl hydrazodiformate is 16466-61-8 and its linear formula is [NHCO2C(CH3)3]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Di-tert-butyl hydrazodiformate with a purity of 97%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or any pharmacopoeial grade.
How should Di-tert-butyl hydrazodiformate be handled safely?
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Di-tert-butyl hydrazodiformate is classified as a warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of contact, rinse thoroughly with water.
How is Di-tert-butyl hydrazodiformate packed and exported?
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Di-tert-butyl hydrazodiformate is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or quote for Di-tert-butyl hydrazodiformate?
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To request a sample or a quotation for Di-tert-butyl hydrazodiformate, please contact our sales team through the website or by phone. We aim to respond promptly to all inquiries.
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