Di-tert-butyl chloromethyl phosphate
Di-tert-butyl chloromethyl phosphate (CAS: 229625-50-7, Formula: C9H20ClO4P) is a specialised organophosphorus compound with a molecular weight of 258.68 g/mol. It serves as a valuable building block in organic synthesis and is particularly useful as a derivatisation reagent in analytical chemistry, including HPLC applications. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- Phosphoric acid di-tert-butyl chloromethyl ester

Organic Synthesis
As a building block, Di-tert-butyl chloromethyl phosphate can be utilised in the construction of more complex organic molecules. Its structure allows for various synthetic transformations, making it a versatile reagent in chemical synthesis.
Derivatisation Reagent
This compound is employed as a derivatisation reagent, particularly in analytical techniques such as High-Performance Liquid Chromatography (HPLC). It helps in modifying analytes to improve their detection or separation characteristics.
Analytical Chemistry
Di-tert-butyl chloromethyl phosphate finds application in analytical chemistry, contributing to methods that require specific chemical modifications for analysis. It is useful in processes involving UV-VIS detection.
| Molecular weight | 258.68 |
|---|---|
| Empirical formula | C9H20ClO4P |
| Assay | ≥85% (HPLC) |
| Storage temperature | −20°C |
| Contains / stabiliser | 5% tributylamine as stabilizer |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Di-tert-butyl chloromethyl phosphate used for?
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Di-tert-butyl chloromethyl phosphate is primarily used as a building block in organic synthesis and as a derivatisation reagent, particularly for HPLC and UV-VIS detection in analytical chemistry.
What are the CAS number and formula for Di-tert-butyl chloromethyl phosphate?
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The CAS number for Di-tert-butyl chloromethyl phosphate is 229625-50-7, and its molecular formula is C9H20ClO4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Di-tert-butyl chloromethyl phosphate with an assay of ≥85% (HPLC). This compound is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Di-tert-butyl chloromethyl phosphate be handled safely?
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Di-tert-butyl chloromethyl phosphate is classified as harmful if swallowed and harmful if inhaled (H302 + H332). Handle with appropriate personal protective equipment (PPE) in a well-ventilated area, following safety recommendations (e.g., Risk Statements 20/21/22, Safety Statements 36/37).
How is Di-tert-butyl chloromethyl phosphate stored and shipped?
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Di-tert-butyl chloromethyl phosphate should be stored at −20°C. It is stabilised with 5% tributylamine. Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample for Di-tert-butyl chloromethyl phosphate?
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To request a quote or sample for Di-tert-butyl chloromethyl phosphate, please contact our sales team through the website or by phone, providing your specific requirements.
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