Di-tert-butyl azodicarboxylate
Di-tert-butyl azodicarboxylate (CAS: 870-50-8), with the molecular formula (CH3)3COCON=NCOOC(CH3)3 and a molecular weight of 230.26 g/mol, is a versatile organic reagent. It is primarily employed in synthetic organic chemistry, particularly in reactions involving C-X bond formation and as a key component in the Mitsunobu reaction. Its effectiveness as a dehydrating agent and oxidant makes it valuable for various chemical transformations.
- IUPAC
- Bis(1,1-dimethylethyl)azodicarboxylate,DBAD,Di-tert-butyl azodiformate,NSC 109889
- Synonyms
- Bis(1,1-dimethylethyl)azodicarboxylateDBADDi-tert-butyl azodiformateNSC 109989
Mitsunobu Reaction Reagent
Di-tert-butyl azodicarboxylate is widely utilised as the oxidant in the Mitsunobu reaction. This reaction facilitates the stereospecific conversion of alcohols into various functional groups, such as esters, ethers, and azides, under mild conditions.
C-X Bond Formation
This compound serves as an effective reagent for forming C-X bonds, specifically in non-halogenation processes. It enables the introduction of various functionalities onto organic molecules through oxidation and coupling reactions.
Oxidising Agent in Synthesis
Beyond the Mitsunobu reaction, Di-tert-butyl azodicarboxylate functions as a general oxidising agent in organic synthesis. It can be employed to oxidise specific functional groups or to facilitate dehydrogenation reactions.
Dehydrating Agent
Its chemical properties allow it to act as a dehydrating agent in certain organic transformations, removing water molecules to promote desired reactions or to drive equilibria.
| Molecular weight | 230.26 |
|---|---|
| Linear formula | (CH3)3COCON=NCOOC(CH3)3 |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Melting point | 89-92 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Greener Alternative Product Characteristics | Catalysis |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Di-tert-butyl azodicarboxylate used for?
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Di-tert-butyl azodicarboxylate (CAS: 870-50-8) is primarily used as a reagent in organic synthesis, notably in the Mitsunobu reaction for the conversion of alcohols, and for C-X bond formation reactions. It also acts as an oxidising and dehydrating agent.
What are the CAS number and chemical formula for Di-tert-butyl azodicarboxylate?
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The CAS number for Di-tert-butyl azodicarboxylate is 870-50-8. Its linear formula is (CH3)3COCON=NCOOC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Di-tert-butyl azodicarboxylate with an assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Di-tert-butyl azodicarboxylate be handled?
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Di-tert-butyl azodicarboxylate is classified as a Warning substance, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, such as a dust mask (type N95 or equivalent), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is Di-tert-butyl azodicarboxylate packed and exported?
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Di-tert-butyl azodicarboxylate is carefully packaged to maintain its integrity during transport and is available for export globally. Specific packaging details are available upon request for bulk orders.
How can I request a sample or quote for Di-tert-butyl azodicarboxylate?
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To request a sample or a quote for Di-tert-butyl azodicarboxylate, please contact our sales team through the website or by phone. Please specify the quantity required and your shipping destination.
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