Di-tert-butyl nitroxide
Di-tert-butyl nitroxide (CAS: 2406-25-9), with the molecular formula C8H18NO and a molecular weight of 145.24 g/mol, is a stable free radical. It is primarily utilised as a spin label in research applications, aiding in the study of localization of lipid microdomains and thermal phenomena, particularly in biological systems. This compound is supplied by Tech Serve Solutions.
![Di-tert-butyl nitroxide ([(CH3)3C]2NO) — chemical structure, CAS 2406-25-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F2406-25-9.png&w=3840&q=75)
Spin Labelling
Di-tert-butyl nitroxide functions as a spin label, a crucial tool in Electron Paramagnetic Resonance (EPR) spectroscopy. This enables researchers to probe molecular environments and dynamics.
Biological Studies
It has been employed in investigating biological systems, such as localizing lipid microdomains within biological membranes and analysing thermal phenomena in tissues like murine stratum corneum.
Radical Chemistry
As a stable radical, it serves as a reagent or reference compound in studies related to radical chemistry and reaction mechanisms involving free radicals.
| Molecular weight | 145.24 |
|---|---|
| Linear formula | [(CH3)3C]2NO |
| Assay | 90% |
| Grade | technical grade |
| Boiling point | 74-75 °C/34 mmHg(lit.) |
| Refractive index | n20/D 1.435(lit.) |
| Storage temperature | 2-8°C |
| Application | Spin label. Has been used in localization of lipid microdomains and thermal phenomena in murine stratum corneum. |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 46 °C / 114.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-22-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Di-tert-butyl nitroxide used for?
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Di-tert-butyl nitroxide is used as a spin label for studying lipid microdomains and thermal phenomena, and in general radical chemistry research.
What are the CAS number and chemical formula for Di-tert-butyl nitroxide?
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The CAS number for Di-tert-butyl nitroxide is 2406-25-9, and its linear formula is [(CH3)3C]2NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Di-tert-butyl nitroxide in technical grade with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Di-tert-butyl nitroxide be handled safely?
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Di-tert-butyl nitroxide is flammable and harmful if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, in a well-ventilated area away from ignition sources.
How is Di-tert-butyl nitroxide packed and exported?
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Di-tert-butyl nitroxide is packed and exported in compliance with relevant transport regulations, identified under UN 1993C 3 / PGIII for shipping.
How can I request a sample or quote for Di-tert-butyl nitroxide?
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To request a sample or a quotation for Di-tert-butyl nitroxide, please contact the Tech Serve Solutions sales team via our website or by telephone.
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