N-(4-Hydroxyphenyl)-arachidonylamide
N-(4-Hydroxyphenyl)-arachidonylamide (CAS: 183718-77-6; Formula: C26H37NO2; MW: 395.58) is a bioactive small molecule primarily known for its role in cell signaling. This compound potentiates the activity of endogenous anandamide by inhibiting its re-uptake into presynaptic membranes. It is supplied as an ethanol solution and is utilised in research concerning neurobiology and cell biology.
- IUPAC
- AM404

Anandamide Reuptake Inhibition
This compound selectively inhibits the carrier-mediated transport of anandamide, thereby potentiating its activity. It acts by blocking the re-uptake into presynaptic membranes without affecting anandamide hydrolysis.
Neuroscience Research
Utilised in studies investigating the endocannabinoid system and its role in neural pathways. It aids in understanding the mechanisms of cannabinoid receptor signalling and related neurological processes.
Cell Signaling Studies
Serves as a valuable tool for researchers exploring cell communication pathways. Its specific action on anandamide transport makes it relevant for deciphering complex cellular signalling cascades.
| Molecular weight | 395.58 |
|---|---|
| Empirical formula | C26H37NO2 |
| Assay | ≥98% |
| Form | ethanol solution |
| Storage temperature | −20°C |
| Application | Potentiates the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. AM404 selectively inhibits the carrier-mediated transport of anandamide without affecting anandamide hydrolysis. |

Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 14 °C / 57.2 °F |
| Transport (UN / ADR) | UN 1170 3 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 16 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|---|
| Gene Information | human ... CNR1(1268), CNR2(1269)mouse ... Cnr2(12802)rat ... Cnr1(25248), Faah(29347), Trpv1(83810) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-Hydroxyphenyl)-arachidonylamide used for?
+
N-(4-Hydroxyphenyl)-arachidonylamide is used to potentiate the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. It is utilised in research related to cell signaling, neuroscience, and cell biology.
What are the CAS number and formula for N-(4-Hydroxyphenyl)-arachidonylamide?
+
The CAS number for N-(4-Hydroxyphenyl)-arachidonylamide is 183718-77-6, and its molecular formula is C26H37NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies N-(4-Hydroxyphenyl)-arachidonylamide with an assay of ≥98%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How is N-(4-Hydroxyphenyl)-arachidonylamide handled and stored?
+
N-(4-Hydroxyphenyl)-arachidonylamide is a flammable liquid and vapour (H225). It requires careful handling, use of appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. It should be stored at -20°C.
How is N-(4-Hydroxyphenyl)-arachidonylamide shipped?
+
N-(4-Hydroxyphenyl)-arachidonylamide is shipped in an ethanol solution and typically packed and shipped on wet ice to maintain its stability during transit.
How can I request a quote or sample?
+
To request a quote or sample of N-(4-Hydroxyphenyl)-arachidonylamide, please visit our website or contact our sales department directly with your inquiry.
▶ Related products

(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology

(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis