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N-(4-Hydroxyphenyl)-arachidonylamide

CAS 183718-77-6C26H37NO2Cell Biology

N-(4-Hydroxyphenyl)-arachidonylamide (CAS: 183718-77-6; Formula: C26H37NO2; MW: 395.58) is a bioactive small molecule primarily known for its role in cell signaling. This compound potentiates the activity of endogenous anandamide by inhibiting its re-uptake into presynaptic membranes. It is supplied as an ethanol solution and is utilised in research concerning neurobiology and cell biology.

IUPAC
AM404
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N-(4-Hydroxyphenyl)-arachidonylamide (C26H37NO2) — chemical structure, CAS 183718-77-6; Life Science, fine chemical supplied by Tech Serve Solutions
Bioactive Small MoleculesCannabinoidsCell BiologyNeurobiologyNeurosciencePharmacologicals More...
01 /Applications

Anandamide Reuptake Inhibition

This compound selectively inhibits the carrier-mediated transport of anandamide, thereby potentiating its activity. It acts by blocking the re-uptake into presynaptic membranes without affecting anandamide hydrolysis.

Neuroscience Research

Utilised in studies investigating the endocannabinoid system and its role in neural pathways. It aids in understanding the mechanisms of cannabinoid receptor signalling and related neurological processes.

Cell Signaling Studies

Serves as a valuable tool for researchers exploring cell communication pathways. Its specific action on anandamide transport makes it relevant for deciphering complex cellular signalling cascades.

02 /Properties
Molecular weight395.58
Empirical formulaC26H37NO2
Assay≥98%
Formethanol solution
Storage temperature−20°C
ApplicationPotentiates the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. AM404 selectively inhibits the carrier-mediated transport of anandamide without affecting anandamide hydrolysis.
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
Danger

Hazard statements

  • H225Highly flammable liquid and vapour

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point14 °C / 57.2 °F
Transport (UN / ADR)UN 1170 3 / PGII
Water hazard class (WGK, DE)2
Hazard codes (EU)F
Risk statements (R)11
Safety statements (S)16

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
183718-77-6
MDL number
MFCD03095721
PubChem substance
24895490
05 /Additional specifications
Shipped Inwet ice
Gene Informationhuman ... CNR1(1268), CNR2(1269)mouse ... Cnr2(12802)rat ... Cnr1(25248), Faah(29347), Trpv1(83810)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is N-(4-Hydroxyphenyl)-arachidonylamide used for?

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N-(4-Hydroxyphenyl)-arachidonylamide is used to potentiate the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. It is utilised in research related to cell signaling, neuroscience, and cell biology.

What are the CAS number and formula for N-(4-Hydroxyphenyl)-arachidonylamide?

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The CAS number for N-(4-Hydroxyphenyl)-arachidonylamide is 183718-77-6, and its molecular formula is C26H37NO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies N-(4-Hydroxyphenyl)-arachidonylamide with an assay of ≥98%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.

How is N-(4-Hydroxyphenyl)-arachidonylamide handled and stored?

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N-(4-Hydroxyphenyl)-arachidonylamide is a flammable liquid and vapour (H225). It requires careful handling, use of appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. It should be stored at -20°C.

How is N-(4-Hydroxyphenyl)-arachidonylamide shipped?

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N-(4-Hydroxyphenyl)-arachidonylamide is shipped in an ethanol solution and typically packed and shipped on wet ice to maintain its stability during transit.

How can I request a quote or sample?

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To request a quote or sample of N-(4-Hydroxyphenyl)-arachidonylamide, please visit our website or contact our sales department directly with your inquiry.

Need N-(4-Hydroxyphenyl)-arachidonylamide in a specific grade or volume?